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pharm exam 1

study guide

QuestionAnswer
Teratogenic -causing developmental defects A-NO RISK B-NO RISK IN ANIMAL STUDY C- LITTLE RISK D- RISK BUT CAN BE USED IN LIFE/DEATH X- RISK OUTWEIGHS BENEFITS
SLUDGE PARASYMPATHETIC SYSTEM S-SALIVATION L-LACRIMATION D-DEFECATION G-GI UPSET E-EMESIS
OTOTOXICITY DAMAGE TO EARS
ONSET, PEAK AND DURATION OF INSULIN ONSET- MINUMUM EFFECTS 5-15 MIN. TAKEN WITH FOOD PEAK- HIGHEST LEVEL 30-90 MIN. ASSESS AFTER AN HOUR FOR HYPOGLYCEMIA DURATION- THE LENGTH OF TIME 3HRS
HALF-LIFE THE TIME IT TAKES FOR 1/2 OF THE ORIGINAL AMOUNT OF THE DRUG TO BE REMOVED FROM THE BODY
NEUROTOXICITY DAMAGE TO THE NERVES
NEPHROTOXICITY RENAL TOXICITY- DAMAGE TO THE KIDNEYS TEST- BUM AND CREATININE
HEPATOXICITY LIVER DAMAGE
PEAK AND TROUGH PEAK- THE HIGHEST CONCENTRATION ON A DRUGS ABSORPTION BLOOD SAMPLE TO DETERMINE TROUGH- LOWEST CONCENTRATION OF A DRUG WHATS BEEN ELIMINATED. TAKEN RIGHT BEFORE NEXT DOSE.
AMINOGLYCOSIDE ANTIBIOTICS NEOMYCIN AND PAPRAMYCIN TAKEN ORALLY TO LOWER BACTERIA IN THE BOWELS. SIDE EFFECTS- BALANCE, URINARY OUTPUT. TINNITUS, PHOTOSENSITIVE, HEARING
PHARMACOKINETIC 4 PHASES ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION
PHARMACOKINETIC PROCESS OF DRUG MOVEMENT TO ACHIEVE DRUG ACTION
NARCS/OPIODS EX. MORPHINE, DEMEROL, OXY, CODEINE, HYDROCODONE TO REVERSE- NARCAN
PENTOTHAL SHORT DURATION, USED FOR RAPID INDUCTION (SURGERY) - KEEP CLIENT WARM -CAN DEPRESS RESPIRATORY
PEDIATRIC PATIENT'S DOSING OF PRINCIPLES -MEDS ARE BASED ON WEIGHT IN KG -THINNER, MORE POROUS SKIN, FASTER TOPICAL ABSORPTION -IM ABSORPTION FASTER& IRREGULAR - 2 YRS HAVE SLOWER METABOLISM -LOWER ENZYME IN LIVER
MEDS FOR MYASTHENIA GRAVES TENSILON- IS USED TO DIAGNOSIS & TREAT MESTINON- TREATS MUST BE TAKEN BEFORE MEALS
ALZHEIMER'S DRUGS ARICEPT, EXELON, COGNEX, RAZADAYNE
POLYPHARMACY MANY DRUGS BY DIFFERENT DOCTORS. INTERVENTION- SUGGEST TO THE PATIENT THAT THEY SHOULD USE THE SAME PHARMACY FOR ALL MEDS.
ELDERLY PHARMACOKINETICS ABSORPTION- LOWER IN GASTRIC ACIDITY (HIGHER pH) ALTERS ABSORPTION OF WEAK ACIDIC DRUGS DISTRIBUTION- LOWER PROTEIN BINDING SITES INCREASE CIRCULATION OD FREE DRUGS METABOLISM- LOWER ENZYME FUNCTION, LOWER DETOXIFYING DRUGS. HIGHER RISK OF TOXICITY. EX
TEST FOR RENAL FUNCTION CREATININE CLEARANCE
BENZODIAZEPINES XANAX, RESTORIL, ATIVAN REVERSAL-ROMAZICON
FLAGYL -AVOID ALCOHOL -TAKE ON AN EMPTY STOMACH
MOTRIN -REDUSES INFLAMMATION -RELIEVES PAIN -FEVER REDUCER ADVERSE: GI BLEEDING
MACRODANTIN TREATS ACUTE/CHRONIC \UTI ADVERSE: SUPERINFECTION, PERIPHERAL NEUROPATHY,HEMOLYTIC ANEMA
AMPHOTERICIN B ANTIFUNGAL- TREATS SYSTEMATIC SUPER INFECTIONS ADVERSE EFFECTS: HYPOTENSION, PARASYTHESIS, THROMBOPHLEBITIS ( INFLAMMATION IN VESSEL WALLS) HIGHLY TOXIC & CAUSE NEPHROTOXCITY & ELECTROLYTE IMBALANCE
OVERDOSE OF URECHOLINE ATROPINE SULFATE
SYNERGISTIC DRUG TWO OR MORE DRUGS GIVEN TOGETHER & COMBINED GIVE A BETTER CLINICAL EFFECT EX)DEMEROL & PHENERGAN- BOTH CAUSE DROWSINESS EX) ALCOHOL & VALIUM- TOGTHER RAISE CENTRAL NERVOUS SYSTEM DEPRESSION
SPINAL ANESTESIA CARE NURSING PROCESS -REMAIN FLAT -INCREASE FLUIDS TO LOWER CHANCES OF SPINAL FLUID LEAKAGE/ COULD CAUSE HEADACHES -MONITOR THE PATIENT FOR HYPERTENSION POST SURGERY
SECONAL A BARBITUATE
TETRACYCLINE -MAY DISCOLOR TEETH -TAKE ON A EMPTY STOMACH -PHOTOSENSITIVE
PENICILLIN -OBTAIN CULTURE BEFORE FIRST DOSE - TAKE 1 HR BEFORE OR 2 HRS AFTER EATING -INTERFERS WITH CONTRACEPTIVES -MAY CAUSE YEAST INFECTIONS
PARKINSONISM MEDS TO BE TAKEN BENZTROPINE (COGENTIN)
ADRENERGIC ANTAGONIST (BLOCKER) DECREASES SYMPATHETIC NERVOUS SYSTEM (LOL) BLOCKS BETA EX)ATENOLOL- TREATS HYPERTENSION ALWAYS CHECK BP & HR
AGONIST ADRENERGIC SYMPATHETIC (INCREASES) EX)EPINEPHRINE- TREATS- HYPERTENSION, ASTHMA, ALLERGIES SIDE EFFECTS- TREMORS, N/V, DIZZINESS ADVERSE: PALPATATIONS, TACHYCARDIA, DYSPEA
CHOLINGERICS AGONIST PARASYMPATHETIC SYSTEM ( INCREASES) EX) URECHOLINE- TRAETS URINARY RETENTION: INCREASES URINE OUTPUT EX) METOCLOPRAMIDE (REGLAN) RAISES GAS EMPTYING EX) PILOCARPINE (PILOCAR) CONSTRICTS PUPILS
ANTICHOLINGERICS PARASYMPATHETIC (DRECREASES) CHOLINGERIC BLOCKER EX) ATROPINE- USED PEROPERATIVELY TO REDUCE SALIVATION, RAISE HR, DILATE PUPULS SIDE: DRY MOUTH, BLURRED VISION, URINARY RETENTION WARNING:DNU ON PATIENT WITH GLAUCOMA
ANTICHOLINGERICS PRECAUTIONS BEWARE OF POSSIBLE OVERDOSE SYMPTOM, MUSCULAR WEAKNESS, LOWER MUSCLE RIDGITY, SALIVATION, HIGHER HR, RELAXED BLADDER CONSTRICTION OF PUPILS, INCREASE BRONICHIAL SECRETION, DECREASE BP
MACRODANTIN & PYRIDIUM WORK TOGETHER ON SOMEONE WHO HAS A UTI. MACRODANTIN0- ANTIBIOTIC MAY TURN URINE BROWNISH RED PYRIDIUM- RELIEF OF PAIN TURNS URINE ORANGE
NURSING IMPLICATIONS- RECIEVING OPIOD ANAGESIA -MONITOR VS FREQUENTLY -RECORD URINARY OUTPUT -CHECK BOWEL SOUNDS FOR LOWER PERISTALSIS -HAVE NARCAN AVAILABLE
Created by: cshadders
 

 



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