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Broncho/Leukotriene

1st year, 2nd semester nursing student, pharmacology test

QuestionAnswer
Bronchodilator/Leukotriene Antagonist montelukast Singulair
Bronchodilator/Leukotriene Antagonist zafirlukast Accolate
Bronchodilator/Leukotriene Antagonist zileuton Leutrol, Zyflo
Bronchodilator/Leukotriene Antagonist Indications Prevention and treatment of asthma
Bronchodilator/Leukotriene Antagonist Actions Inhibit bronchocostriction by antagonizing the effects of leukotrienes
Bronchodilator/Leukotriene Antagonist Contraindications Acute asthma attack
Bronchodilator/Leukotriene Antagonist Life Span OB Lactation: satefy not established. Pedi: not established for <1 year
Bronchodilator/Leukotriene Antagonist Drug interactions Use of zafirlukast or zileuton with warfarin may increase PT Erythromycin and theophylline decrease bioavailability of zafirlukast. Montelukast has decreased bioavailability when taken concurrently with phenobarbital or rifampin.
Bronchodilator/Leukotriene Antagonist Side Effects Headache and dyspepsia most common Pedi: otitis and sinusitis
Bronchodilator/Leukotriene Antagonist Implications and teaching Montelukast- evening for asthma, any time of day for allergies. Have family and patient alert for agitation, panic attacks, depression, and suicidal thoughts. Zafirlukast- take on empty stomach due to food decreasing absorption.
Created by: Carebear71