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OI

Opportunistic Infections

InfectionPPX/TxGenericBrandSide EffectsMonitoring
PCP TX Pentamidine Pentam leukopenia, hypotension, thrombocytopenia, sterile abscess, metallic taste, hypocalcemia, phosphate (hypo or hyper), Intense nephrotocin, pancreatitis, hypo/hyperglycemia SCr/BUN, Amylase/Lipase, serum glucose, CBC (rare)
PCP Tx Primaquin/Clindamycin Primaquin/Clindamycin n/v/d, ab pain, pseudomembranous colitis, rash, granulocytopenia, hemolytic anemia, methehmoglobinemia CBC, Methemaglobin G6PD, diarrhea (BUN/SCr, electrolytes, toxic megacolon)
CMV Tx Ganciclovir Cytovene granulocytopenia, thrombocytopenia, neutropenia, anemia, ha, confusion, renal SCr (dosing), CBC
CMV Tx Valganciclovir Valcyte granulocytopenia, thrombocytopenia, neutropenia, anemia, ha, confusion, renal SCr (dosing), CBC
CMV Tx Foscarnet Foscavir renal, hypokalemia, hypomagnesemia, hyponatremia, phosphate, hypocalcemia, n/v, anemia, ha, cns SCr/BUN, Na, K, Mg, Ca, Phos, CBC
CMV Tx Cidofovir Vistide nephrotoxic! Scr/BUN, urine, proteinuria
Toxoplasmosis coktail w/ leucovin and (sulfadiazine OR clinda OR azithro OR atovaquone) Pyrimethamine Pyrimethamine leuko/thrombocytopenia, pancytopenia, n/v, ha, malaise (must use w/ leucovin) CBC
Toxoplasmosis cocktail w/ pyri & leuco Sulfadiazine Sulfadiazine rash, n/a, anemia, neutropenia, peripheral neuropathy CBC, SCr
Toxoplasmosis cocktail w/ (pyri & leuco) OR azithro Clindamycin Clindamycin pseudomembranous colitis, n/v/d, rash diarrhea (BUN/SCr, electrolytes, toxic megacolon)
Toxoplasmosis cocktail w/ pyri & leuco Azithromycin Azithromycin diarrhea, tinnitus, ab cramping, nausea
Toxoplasmosis cocktail w/ pyri & leuco Atovaquone Atovaquone tastes bad, n/v/d
Toxoplasmosis PPX/Tx Sulfa/Trimeth Bactrim rash, n/v, hyperkalemia, renal dysfunction, bone marrow CBC, SCr/BUN, K, Na, Albumin
Mycobacterium (MAC) PPX/Tx Azithromycin Azithromycin diarrhea, tinnitus, ab cramping, nausea
MAC (Mycobacterium) PPX Rifabutin Mycobutin rash, discolored urine/feces/tears/saliva, n/v, neutropenia, leukopenia LFT, CBC
MAC PPX/Tx Clarithromycin Clarithromycin n/d, loss of hearing, dyspepsia, bad taste
MAC Tx Ethambutol Ethambutol anorexia, n/v, fever, malaise, ha, dizziness, peripheral/opic neuritis SCr, CBC
MAC Tx Amikacin or Streptomycin Amikacin or Streptomycin renal dysfunction, ototoxicity, pain on injection SCr
MAC Tx FQ's (cipro, levo, moxi) FQ's nausea, confusion, dizziness, hyper/hypo glycemia, QT prolongoation
Cryptosporidium Tx Paromomycin Hymatin (doesn't really work)
Crypto Tx (DOC) Nitazoxanide Alinia n/v/d, ab pain, ha
Kaposi Sarcoma (KS) Tx HAART
PCP (Pneumocystis Carnii Pneumonia) PPX (DOC) Sulfa/Trimeth Bactrim (DS daily, SS daily, or DS TIW) rash, n/v, diarrhea, anemia, thrombocytopenia, agranulocytosis, hyperkalemia CBC, SCr/BUN, K, Na, Albumin
PCP Tx Sulfa/Trimeth Bactrim (15-20mg/kg/dy q6-8h rash, n/v, diarrhea, anemia, thrombocytopenia, agranulocytosis, hyperkalemia CBC, SCr/BUN, K, Na, Albumin
PCP PPX/Tx Dapsone Dapsone agranulocytosis, aplastic anemia, methemoglobinemia CBC, SCr/BUN, K, Methemaglobin G6PD
PCP PPX/Tx Atovaquone Mepron tastes bad, n/v/d
Created by: 1450725958