Busy. Please wait.
Log in with Clever

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever

Username is available taken
show password

Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't Know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how


Infectious Disease

PCNs MOA inhibit cell wall synthesis
Vancomycin MOA (glycopeptide) - inhibit peptidoglycan cross-linking
Aminoglycosides MOA (tobramycin, gentamycin, neomycin) - stop mRNA translation
Quinolones MOA DNA gyrase inhibitors: inhibit bacterial DNA synthase
Macrolides MOA inhibit 50S ribosome => decreased protein synthesis
Tetracyclines MOA Protein synthesis inhibitor: act on 30S subunit
Classes of Abx that are cell wall synthesis inhibitors PCNs. Cephalosporins. Monobactams (aztreonam). Carbapenems. Vanco
Classes of Abx that are protein synthesis inhibitor Aminoglycosides. Tetracyclines. Macrolides. Choramphenicol. Clindamycin.
Antimetabolites = Sulfonamides
Protein synthesis inhibitor MOA Bind to ribosomes and prevent protein synthesis => cell death & decreased replication
1st gen cephalosporins activity Cefazolin & cephalexin: gram pos (Staph / Strep), skin infxn, surg ppx
2nd gen cephalosporins activity Cefaclor, cefoxitin, cefuroxime: more GN activity (E coli, Klebsiella, Proteus, H flu); intra-abd infxn
3rd gen cephalosporins activity Ceftazidime (Pseudomonas), ceftriaxone, cefdinir: primarily GN activity (including Pseudomonas, Enterobacter, Serratia), some Gm Pos. Tx N meningitides
4th gen cephalosporins activity Cefepime: broad GN activity including resistance to beta-lactamase; Pseudomonas. Less GP
5th gen cephalosporins activity Ceftaroline: against selected Staph spp (MSSA skin only), some Strep spp, some GN (H flu, Klebsiella, E coli)
Monobactam activity AztreonamL GNR (Pseudomonas, Serratia, Klebsiella)
Carbapenem activity Broad vs anaerobes, esp PCN-resistant pneumococcus & Enterobacter
Aminoglycosides activity Gentamicin, tobramycin, amikacin: GN enteric bacteria (E coli, Proteus, Klebs, Serratia, Enterobacter)
Tetracyclines activity GP & GN including atypical PNA bugs, Rickettsia, Lyme disease
Macrolides activity GP; atypical PNA bugs, H pylori
Antimetabolites (sulfonamides) activity GP & GN; esp E coli, Salmonella, Shigella, Enterobacter
Trimethoprim is used to tx: combined with sulfa drug to tx UTIs, PCP PNA, Shigella, Salmonella, URIs
Quinolones activity Aerobic GNR (Pseudomonas, Neisseria); Anthrax
NRTIs MOA Nucleoside reverse transcriptase inhibitors: inhibit HIV reverse transcriptase. AZT, didanosin (ddI), lamivudine (3TC), stavudine (d4T)
NNRTIs MOA Non-nucleoside reverse transcriptase inhibitors: inhibit reverse transcriptase. Nevirapine, delavirdine, efavirenz
Protease inhibitors MOA Inhibit production of mature virions, inhibit replication. Ritonavir, indinavir
Penicillin is used to tx (3): Syphilis, GBS (in PG female), N meningitides
Beta-lactamase PCNs include: nafcillin, oxacillin, dicloxacilin, cloxacillin, and Cillian Murphy
Beta-lactamase PCNs tx these types of infxn (3) Staph spp (not MRSA), skin infxn, osteomyelitis
Created by: Abarnard
Popular Pharmacology sets




Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
restart all cards