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mo system

integumentry and endocrine system notes and def.

QuestionAnswer
Testes produces testoterone and produces spermatozoa
penis largest part of the uretha
prostate gland -Produces different types of hormones
semen Consist of sperm and other secretions
luetnizing hormone -Stimulates the formation of testosterone
Follicle Stimulating hormone (FSH) Stimulates the production of sperm
Testosterone -Regulates metabolism and protein anabolism which results in growth of bone and muscle
Gonorrhea -Inflammation of the genital tract mucous membranes
Genital Herpes Viral infection
Amenorrhea -Absences of menses
Menopause -End or reproductive capability
Benign tumors (non-cancerous
Fibroids -Correct name is myoma and are common tumors of the uterus
Malignant tumors (cancerous)
Breast cancer the most common malignant disease in women
Malignant tumors (cancerous) -Most common cancer in women is cancer of the endometrium
Ovarian cancer is the leading cause of cancer death in women
Pelvic Inflammatory disease (PID) - May cause infertility
Prostatic hypertrophy Rarely cause symptoms before age 40 usually seen in men over age 60
Androgens Primary testosterones are male sex hormones used for replacement therapy
Terazon and doxazoin -Used to treat BPH
Impotence Erectile dysfunction
causes on impotence -Psychological factors, stress, depression
treatment of impotence -Yohimole,silenfil (viagra), vardenafi(levitra
Ovaries -Go nads, small almond shape
Fallopian tubes -Fertilization usually takes place in the fallopian tube
Vagina -Receives sperm during intercourse an exit for menstrual blood flow an as a birth canal
Mammary glands (breast) -Prolactin from the anterior pituitary causes the actual synthesis of milk after pregnancy
Three phases of Menses 1.menstrual, follicular, luteal
-Leuprolide (lupron) -Available in depot forms that is given either monthly or every 3 months
Estrogen -Produced by ovaries
Natural steroid estrogens include Estradoil
Lowest effective dosages of estrogen should be administered for the shortest period of time to reproduce the possibility of side effects
Side effect of over dosage of estrogen hypertension
DES-dietary stillbestrol -Synthetic nonstredical estrogen used primarily as an antiplastic agent
-Progesterone and progestin -Produces biochemical changes in the endometrium to prepare for the implantation and nourishment of the embryo
-Megace -Treats breast and eudiometrical cancer
Oral Contraceptives -Generally a combination of estrogen and progestins
Combination of estrogen/progesin are divided into 3 groups Monophonic,Biphasic (Lo oral), -Triphasic
-Monophonic Fixed ratio taken for 21 days
-Biphasic (Lo oral) -2 different amounts of progestin (ortho-novum 10/11)
-Triphasic -Most closely stimulates the normal estrogen and progesterone levels during the menstrual cycle (ortho-novum 7/7/7)
Meddroxy progestone (Depo-Provera) Given IM (intermuscally) every 3 months to prevent conception
Ortho-evra 1st birth control patch approved by FDA
Progestin for abnormal uterine bleeding cause by hormonal imbalance
Long acting progestin Meddroxy progestone (Depo-Provera)
distribution drug is distributed to the various tissues of the body
distribution is affected by protien plasma binding, blood flow, blood brain barrier
contusion traumatic brusing (someone has been choked)
popules firm raised lesions (chickenpox)
vesicles blister or sac filled with clear fluid
pustle vesicle filled with pus (somekind of an infection)
exacerbation word that refers to flare ups of chronic disorders (acne)
dermatis inflamation of the skin
sunburn uv ratiation burn
burns injuries are on one or more layers of skin are damaged or destroyed
first degree burn damaged is limited to epidermis (stove burn)
second degree burn the damage is to the epidermis and dermis (most painful)
third degree burn epidermis and dermis are damaged, less painful because nerve ending are buried away
impetigo highly contagious disease that is caused by streptococcal or staphycocaccal infection
athletes foot fungal infection of the skin
basal cell carcinoma cancer of the skin, looks like a sore that wouldn't heal
decubitis ulcers bedsores
prutitis another term for itching
pediculsis lice (dont jump but crawl)
disorders of the thyroid hyperthrodism, hypothrodism
specific drugs for thyroid infection levothrooxie (synthroid), liothromine (cytome), liotrix (thyrotar)
parathyroid gland four small bodies embedded in the posterothyroid
parathroid hormone (PTH) raises serum calcium levels by promoting a release of calcium from bones
hydroxychole calciferol increases absorption of calcium from small intestine
alendronate (fosmax) indicated for the treatment of post-menopausal osteoporosis
adrenal medulla produces adrenalin,
epinephrine adrenaline
non-epinephrine non adrenaline
adrenal cortex produces glucocorticoids
mineralocorticoids regualtes h20 and electrolyte balance
disorders of adrenal cortex hypofunction , addison disease
addisons disease life threating deficency of glucocontcoids and mineralocorticoids
pancreas endocrine and exocrine gland
exocrine function is mainly to produce digestive enzymes
endocrine function produces beta and alpha cells
beta cells produce insulin
alpha cells produce glucagon
diabetic ketacidosis a complication of diabetes mellitus caused by the build up of products of fat metabloism (keatones) which occurs when glucose is not avaliable as a fuel source for the body
insulin dependant also called type 1 diabetes or juvenille onset
non insulin dependant type 2 diabetes, or adult onset
which is the injectible type of diabetes type 1
types of insulin porcine, recombinant, bovine
bovine beef
recombinant human
porcine pork
sulfaryureas lower blood glucose levels by increasing the releaseof insulin from the pancreas
glyburide diabetic, mironase
endocrine have no ducts, secrete directly into the bloodstream
exocrine have ducts that carry out secretions
hormones regulate growth metabolism, reproduction, and numerous other process
types of hormones protien, steroids
protien hormones made of amino acid
steroids hormones derived from lipids (fats)
major glands pituitary, thyroid, parathyroid, adreneal, pancreas, ovaries, testes, pineal
minor glands kidney, thymus, placenta
pitutary gland called the master gland
pitutiary gland controls actions of other glands
growth hormone (GH) somatropin is another name for
growth hormone (GH) acts throughout the body to promote protien use which is essiental to growth
thyrad stimulating hormone (TSH) Thyrotropin
thrad stimulating hormone stimulates the throid
adrenocorticotropic hormone (ACTH) stimulates the adrenal cortex
prolactin stimulates the production of milk
gonatropins sex hormones
lutenizing hormone causes ovolation
Pituitary gland is important b/c controls actions of all glands
antidivretic hormone (ADH) vaso pressin
antidivretic hormone (ADH promotes reabsorption of water form kidney tables therby decreasing water excretion
disorders of the pituitary gland gigantism, dwarfism, acromegaly
acromegaly results form excess growth hormone in adulthood
thryoid gland largest gland, regualtes metabolism
calcitonin decreases serum calcium by simulaing depostion in the bones
glands produce hormones
megitindes a new class of drugs that affect insulin release and work on the pancreas to promote insulin secretion
bigunides decrease glucose production by the liver
epidermis outermost layer of skin, cells constantly divide, made of two layers
dermis true skin
dermis framework of connective tissue adn contains many blood vessels nerve ending and glands
sabaceous layer connects the skin to the surface of the muscles
sudorterous gland sweat gland, help maintain body temp.
sabacous gland oil gland, open to hair follicies
secrete sebum oil which lubricates the skin and hair
disorder of sabacous gland putule-pimple- infected sabacous gland
nail protective structure made of keratin
functions of the skin protection, regulate body temp, communication, excretion of waste
melanin color or everything that is colored on body is because of
disorders of the skin albino
albino hereditary default causing a lack of melanin
juandice yellowish discoleration
erythema reddness of skin
cyanosis blusih discoleration due to lack of oxygen
trauma accidental break in the skin
lesion any wound sore or injury
excoration a wound that is evidence of scratching
avulsion forcible ripping of skin, may accompany machinary accidents or animal bites
pharmacology study of drugs
pharmakanetics study of the process of absorpiton, distribution, metabolism adn excreation
pharmatheraputics study of the use of drugs in treating disease
drug any chemical substance that produces a change in body function
prescription drug drug that requires an order from a physician
OTC over the counter, drug cannot be purchase without letter from doctor
dose the exact amount of drugs that is administered
bioavaliability the percentage of drugs that is actually absorbed into the bloodstream
duration of action the length and time a drug is effective
mechanism of action MOA
mechanism of action explanation of how the drug works
site of action location in the body where the drug exerts its theraputic effect
indication what the drug is used for
contradiction when a drug should not be used
systemic worksthroughout the body
local works in specific area in body
theraputic intended effect
side effect unintened effect
adverse effect harmful, unintended effect
sources of drugs plant, animals, mineral, chemicals
origanal source of drugs plant
chemical scientific name
generic non proprietary
brand proprietary (tylenol )
absoption drugs that must be dissolved before it can be absorbed
metabolism chemical alteration of drugs other compounds in the body
excretion elimination of drugs from the body
3 types of excretion rino, rasportory, gastrotestuanal
drug topic red and blue book guide to prices, products and includes manufacter, packaging size, strength, wholesale and retail prices
schedule 1drugs highest abuse potential, no accepted medical use (heroin)
schedule 2 drugs highest abuse potential, no accepted medical use (morphine)
schedule 3 drugs moderate abuse potential (tylenol 3)
schedule 4 drugs low abuse potential (valum, zanax)
schedule 4 drugs limited abuse potential (robitussin ac)
theraputic index relative safety of the drug
distribution is affected by protien plasma binding, blood flow, blood brain barrier
infertility cant reproduce
annovulation absence of ovulation
causes of infertility ther cervical factor
cervical factor refers to the ability of the cervix to nurture and transport sperm into the female reproductive tract
causes and contributing factors of the cervical factor intraverine exposure to DES, previous cone biopsy, infection
biopsy check for cancer
the ovultary factor accounts for about 1/5 of all cases of infertility
causes of ovultary factor heavy serious exercise/dieting, hyperprolactinema, polycystic ovarian syndrome, premature ovarian failure (menopause)
the uterine factor refers to any abnormalties of the uterus or uterine lining
causes of the uterine factor fibroids,abnormally lining,poor endometrial lining, endometrosis
endometrosis presence and growth of the endometrium ouside of the uterus
drugs that treat female infertility clomphene(clomid), urofollitripin(metrodin)
why is estrogen so important after bleeding ceases in the menstrual cycle estrogen helps repairs the endometrium
basal layer deepest layer of skin, cells divide
stratum corneum cells die and become keratin
hydrocortisone most important glucocortcoid hormone
hydrocortisone increases the ability of cells to make sugar out of fat and protiens, also called cortisol
cortisol regulates the quantity of sugars, fats and protien in blood and cells
Created by: tellmo4show
Popular Pharmacology sets

 

 



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