Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

HIV ARV therapy

Zidovudine NRTI
Abacavir NRTI
Lamivudine NRTI
Emtricitabine NRTI
Didanosine NRTI
Stavudine NRTI
Tenofovir NRTI (nucleoTide)
Class toxicities: lactic acidosis, hepatomegaly NRTI
AE: mostly myelosuppression; anemia, neutropenia, HA, malaise ZIdovudine (AZT)
BBW: non-cirrhotic portal HTN; AE: pancreatitis, CD4 toxicity with Tenofovir (TDF) Didanosine (ddI)
AE: peripheral neuropathy, mitochondrial toxicities, lipoatrophy Stavudine (d4T)
benign drugs with little toxicities; HA, N/V/D Lamivudine (3TC) Emtricitabine (FTC)
hypersensitivity--check allele; doesn't work viral load >100,00, penetrates CNS well Abacavir (ABC)
renal dysfunction--Fanconi's syndrome Tenofovir (TDF)
drugs with activity against HBV Tenofovir Lamivudine Emtricitabine
Efavirenz NNRTI
Nevirapine NNRTI
Delavirdine NNRTI
Etravirine NNRTI
Rilpivirine NNRTI
class toxicites: hepatotoxicity, rash NNRTIs
K103 mutations is responsible for resistance in these ARVs Efavirenz Nevirapine Delavirdine
Contraindicated with PPIs Rilpivirine
Atazanavir PI
Darunavir PI
Nelfinavir PI
Saquinavir PI
Ritonavir PI
Indinavir PI
Lopinavir PI
Tipranavir PI
Fosamprenavir PI
AE: Jaundice, scleral icterus, cholelithiasis, nephrolithiasis, requires acidic pH Atazanavir
AE: N/V/D; take with food to increase bioavail Darunavir
rarely used; really bad diarrhea Nelfinavir
rarely used; prolong QT interval Saquinavir
not an active PI anymore; pharmaco-enhancer Ritonavir
not used often; nephrolithiasis Indinavir
has Ritonavir in formulation; good pregnancy data Lopinavir
salvage drug--higher dose; AE: intracranial bleed Tipranavir
Raltegravir Intergrase inhibitor
AE: severe rash, CPK Raltegravir
Maraviroc Entry inhibitor
must be CCR5 dominant Maraviroc
BBW: hepatotoxicity Maraviroc
Fusion inhibitor; last line therapy; no DDI because it's a very large peptide Fuzeon
Sulfa allergy caution use of: Darunavir Fosamprenavir Tipranavir
AE: depression (Psychiatric disorders), insomnia, HA, rash Rilpivirine
Created by: simpsonan



Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards