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GI System
Test 5
Question | Answer |
---|---|
Antacid Systemic Drug | Baking Soda |
Antacid Systemic Action | Soluable in gastric & intestinal secretions & readily absorbs; capable of altering electrolyte balance producing systemic alkalosis & rebound hyperacidity |
Nonsystemic Antacids Drugs (3) | Maalox, MOM, Mylanta |
Nonsystemic Antacids Action | Soluable in gastric & intestinal secretions & readily absorbs; capable of altering electrolyte balance producing systemic alkalosis & rebound hyperacidity;neutralizes acidity |
Nonsystemic Antacid S/E (2) | diarrhea & constipation |
Nonsystemic Antacid NI (5) | Dont use all the time; block absorption of drugs; dont take drugs w/in 2hrs before/after antacids-no salt added; shake well take w/h20; chew tablet &take w/h20 |
H2 Receptor Inhibitor Drugs (3) | Tagament, Zantac, Axid |
H2 Receptor Inhibitor Action | Inhibit action of histamine at H2 receptor cells in stomach, which reduces secretion of gastric acid |
H2 Receptor Inhibitor S/E (5) | headache, confusion, hallucinations, drowsiness, diarrhea |
Drugs that Protect Muscosa (2) | Carafate & Cytotec |
Cytotec Action | Inhibits production of gastric acid & has muscosal protective propertities |
Cytotec Use | Prevents gastric ulcers in pts taking NSAIDS |
Carafate Action | When swallowed, drug binds w/protein molecules to form a viscous(thick & sticky) substance that buffers acid, that protects muscosa doesnt stop gastric secretions |
Carafate NI | 30min-1hr before meals on empty stomach; fruit,fiber,fluids |
Gastric Acid Pump Inhibitor Drug | Prilosec |
Gastric Acid Pump Inhibitor Action | Surpress gastric acid secretion by block final step in production of gastric acid by gastric muscosa |
Antiflatulants Drug | Mylicon |
Antiflatulant Action | Defoaming action that disperses & prevents formation of muscous surrounding gas pockets in intestines (gas) |
Drugs that increase GI tone & motility Drug | Reglan |
Drugs that increase GI tone & motility Action (3) | Increase motility of GI tracts; increase production of secretions; increase strengths of contractions resulting in faster emptying time of gastric contents into small intestine |
Antiemetic Drug | Zofran |
Antiemetic Action | Act on vomiting center |
Antiemetic Uses (2) | Prevent N/V related to use of anticancer drugs; post-op N/V-major use |
Antiemetic S/E (5) | Headache; fatigue; drowsiness; constipation; sedation |
Drug used in Poisoning | Syrup of Ipecac |
Drug used in Poisoning Action | Caused by location irritation of stomach & by stimulation of vomiting center of medulla |
Drug used in Poisoning (2) | Empty stomach contents rapidly when ingesting poisons or drug overdose; shouldnt be used in pt swallowed a corrosive acid or petroleum product |
Drugs that act on Intestine - Laxative/Irritant/Stimulant Drug | Dulcolax |
Drugs that act on Intestine - Laxative/Irritant/Stimulant Action (2) | Act directly on intestine causing irritation that promotes peristalsis & evacuation; PO form & suppository all found in fridge - will start to melt at room temp - pt needs to be on left side & used water jelly |
Bulk-forming Drug | Metamucil |
Bulk-forming Action | Cause water to be retained w/in stole, increase bulk that stimulates peristalsis |
Bulk-forming Use | Laxative act in 12-24 hours, but may take up to 72 hrs |
Bulk-forming NI | Measure according to Dr order, take large glass of water or juice & bulk go to pt w/spoon & ask if ready to take, put in water, & drink right away. stir enough to mix then more h20, cant let sit b/c it becomes thick |
Fecal Softener Drug | Colace |
Fecal Softener Action (3) | Draw h20 into stole causing it to soften may take up to 72 hours to work; slow acting; take on daily basis |
Lubricant/Emollient Drug | Agoral(Mineral Oil) |
Lubricant/Emollient Action (3) | Lubricates intestinal wall & softens stole; if used frequently it will inhibit absorption of fat soluable vitamins A,D,E,K; mineral oil coats |
Antidiarrheal Drugs (3) | Immodium, Kaopectate, Lomotil |
Antidiarrheal Actions | acts directly on muscle wall of bowel to slow motility; Lomotil - also related to opiods dependence |
Antidiarrheal Use | Relieve acute diarrhea |
Saline Drugs (2) | MOM & Citrate of Magnesia |
Saline Action (2) | Hypertonic compounds attract/pull h20 into intestine from surrounding tissue; increased h20 distends bowel, causing peristalsis - work in 1-3 hrs |