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Movement Disorders
Drug | MOA | USE | AE/BB | Contra/Inter | Monitor/Pearls |
---|---|---|---|---|---|
ropinrole (requip) | Dopamine receptor agonist (selective D2) | delay need for l-dopa Adv PD (adjunct) | |||
ropinrole (requip) | Dopamine receptor agonist (selective D2) | delays l-dopa tx; adv PD; RLS | dizziness, hallucinations, insomnia | cipro inc serum lvl | BP |
benztropine (cogentin) | inihibts indirect pathway from striatum | ||||
Levodopa (L-Dopa) | increases dopamine lvls | PD | Dyskinesia | narrow-angle | |
Carbidopa/levodopa (Sinemet) | C=inhibits LAAD ->inc amt of levodopa entering brain | PD | Dyskinesia | use with MAOI within 14 days | |
bromocriptine (parlodel) | Dopamine receptor agonist | Adv PD | nausea, somnolence | dose related; orthostatic hypotension; P=do NOT require | |
pramipexole (mirapex) | Dopamine receptor agonist | PD; Restless leg | nausea, somnolence | cimetidine inhibits renal excretion |