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Mood Disorder Protot

Mood Disorder Prototypes

NameTherapeutic ClassPharmacologic Class
Sertraline(Zoloft) Antidepressant selective serotonin reuptake inhibitor
Phenelzine(Nardil) Antidepressant Monoamine oxidase inhibitor (MAOI)
Lithium(Eskalith) Mood stabilizing drug; bipolar affective disorder drug Glutamate inhibitor; serotonin receptor antagonist
Methylphenidate (Ritalin) ADHD Drug CNS stimulant
imipramine mechanism of action to inhibit reuptake of norepinephrine and serotonins
imipramine primary use for major depression
imipramine adverse effects orthostatic hypotension, sedation and anticholinergic effect; rarely, cardiac dysrhythmias
sertraline MOA to slow the reuptake of serotonin
sertraline primary use depression
sertraline adverse effects sexual dysfunction, nausea, headache, weight gain, anxiety, insomnia
sertraline less common side effects sedation, anticholinergic effects, sympathomimetic effects
phenelzine MOA to decrease effectiveness of monoamine oxidase
phenelzine primary use for depression
phenelzine adverse effects orthostatic hypotension, headache, insomnia, and diarrhea; Also interact with a large number of foods and other medications Hypertensive crisis can result from interaction of MAOIs and food containing tyramine
Lithium MOA Work by transporting sodium across cell membranes, affects sodium transport across cell membranes, Alteration of ion transport in muscle and nerve cells, Increased receptor sensitivity to serotonin `
Lithium primary use bipolar disorder; treat manic episodes in bipolar psychosis
Lithium interactions Increase lithium level with thiazides, methyldopa, haloperidol, NSAIDs, antidepressants, theophylline, phenothiazines
Lithium side effects/adverse reactions excessive loss of sodium, Headache, drowsiness, dizziness,hypotension, restlessness, slurred speech, dry mouth, metallic taste, tremors,muscle weakness, GI distress, edema of hands and ankles, increased urination, dysrhythmias, blood dyscrasias, nephrotox
Methylphenidate MOA heightens awareness, increases focus, Acts on cerebral cortex, reticular activity system
Methylphenidate Primary use to treat attention-deficit/hyperactivity disorder (ADHD), fatigue, narcolepsy
Methylphenidate Adverse effects insomnia, nervousness, anorexia, weight loss
Methylphenidate interactions Caffeine may increase effects Decrease effects of decongestants, antihypertensives, barbiturates May alter insulin effects
Imipramine(Tofranil) Antidepressant; treatment of nocturnal enuresis (bed wetting) in children Tricyclic antidepressant
Created by: libbygrace7