click below
click below
Normal Size Small Size show me how
Mood Disorder Protot
Mood Disorder Prototypes
Name | Therapeutic Class | Pharmacologic Class |
---|---|---|
Sertraline(Zoloft) | Antidepressant | selective serotonin reuptake inhibitor |
Phenelzine(Nardil) | Antidepressant | Monoamine oxidase inhibitor (MAOI) |
Lithium(Eskalith) | Mood stabilizing drug; bipolar affective disorder drug | Glutamate inhibitor; serotonin receptor antagonist |
Methylphenidate (Ritalin) | ADHD Drug | CNS stimulant |
imipramine mechanism of action | to inhibit reuptake of norepinephrine and serotonins | |
imipramine primary use | for major depression | |
imipramine adverse effects | orthostatic hypotension, sedation and anticholinergic effect; rarely, cardiac dysrhythmias | |
sertraline MOA | to slow the reuptake of serotonin | |
sertraline primary use | depression | |
sertraline adverse effects | sexual dysfunction, nausea, headache, weight gain, anxiety, insomnia | |
sertraline less common side effects | sedation, anticholinergic effects, sympathomimetic effects | |
phenelzine MOA | to decrease effectiveness of monoamine oxidase | |
phenelzine primary use | for depression | |
phenelzine adverse effects | orthostatic hypotension, headache, insomnia, and diarrhea; Also interact with a large number of foods and other medications Hypertensive crisis can result from interaction of MAOIs and food containing tyramine | |
Lithium MOA | Work by transporting sodium across cell membranes, affects sodium transport across cell membranes, Alteration of ion transport in muscle and nerve cells, Increased receptor sensitivity to serotonin | ` |
Lithium primary use | bipolar disorder; treat manic episodes in bipolar psychosis | |
Lithium interactions | Increase lithium level with thiazides, methyldopa, haloperidol, NSAIDs, antidepressants, theophylline, phenothiazines | |
Lithium side effects/adverse reactions | excessive loss of sodium, Headache, drowsiness, dizziness,hypotension, restlessness, slurred speech, dry mouth, metallic taste, tremors,muscle weakness, GI distress, edema of hands and ankles, increased urination, dysrhythmias, blood dyscrasias, nephrotox | |
Methylphenidate MOA | heightens awareness, increases focus, Acts on cerebral cortex, reticular activity system | |
Methylphenidate Primary use | to treat attention-deficit/hyperactivity disorder (ADHD), fatigue, narcolepsy | |
Methylphenidate Adverse effects | insomnia, nervousness, anorexia, weight loss | |
Methylphenidate interactions | Caffeine may increase effects Decrease effects of decongestants, antihypertensives, barbiturates May alter insulin effects | |
Imipramine(Tofranil) | Antidepressant; treatment of nocturnal enuresis (bed wetting) in children | Tricyclic antidepressant |