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GU System
Pharm
| Question | Answer |
|---|---|
| Thiazide & Agents Drugs (2) | Hydrochlorothiazide (HCTZ) & Zaroxylyn |
| Thiazide & Agents Action | Inhibit reabsorption of sodium & chlroide ions in the distal tubule of nephron, which results in excretion of sodium, chloride and water |
| Thiazide & Agents Interventions (6) | Give in early AM, labs, high K+ supplement, no alcohol, sunblock, rise slowly |
| Loop Diuretics Drugs (2) | Bumex & Lasix |
| Loop Diuretic Actions (3) | Inhibits sodium & chloride reabsorption from ascending limp of the loop of Henle, excrete K+,sodium,chlroide,phosphate, magnesium & Bicarbonate, cause vasodilating affect & increase renal blood flow |
| Loop Diuretic Uses (3) | Hypertension, Pulmonary edema & Generalized edema |
| Loop Diuretic S/E (4) | Electrolyte imbalance, dizziness, photosensitivity, hypotension, muscle cramps |
| Loop Diuretic NI individual | Bumex - most powerful (1mg Bumex=1mg Lasix), Lasix - most common, 8-10x more powerful than thiazide family, treat CHF, pt w/ CHF also recieves Digoxin, careful supervision |
| Carbonic Anhydrase Inhibitors Drugs (2) | Diamox, Napatazane |
| Carbonic Anhydrase Inhibitor Action | Inhibit enzyme carbonic & hydrase in kidney, which results in excretion of sodium, potassium, bi-carbonate, water |
| Carbonic Anhydrase Inhibitor Uses (2) | Treats glacoma, Diuretics decrease production of aqueous humor, which in turn decreases intraoccural pressure |
| Osmotics Drugs (2) | Osmitrol & Urivert |
| Osmotics Action | Inhibit tubular reabsorption of water & electrolytes |
| Osmotic Interventions (4) | Monitor VS & level of consciousness, monitor labs, monitor urine output, monitor electrolytes |
| Potassium Sparer Drugs (3) | Aldactone, Aldactazide, Dyrenium |
| Potassium Sparer Action | Antagonises action of aldosterone (blocked) - sodium and water are excreted |
| Aldactone vs Aldactazine & Their goal | Aldactone is potassium sparer; Aldactazine balances & is a combo drug of aldactone & HCTZ; Both hope to balance out potassium |
| Potassium Sparer S/E (4) | Hyperkalemia, gastritis, drowsiness, lethargy |
| Potassium Sparer Intervention (Dyrenium) | Report potassium levels higher than 5 - no salt substitute because its made of potassium |
| Drugs used to treat UTI - Sulfonamide Drug | Bactrim |
| Drug used to treat UTI - Sulfonamide Action | Treat acute UTI & acute Otitis Media (ear infection) |
| Drug used to treat UTI - Sulfonamide S/E (4) | Crystaluria, hematuria, N/V, headache |
| Urinary Antiseptic Agents - Quinolone Drug | Cipro |
| Urinary Antiseptic Agent - Quinolone Use | Treats acute UTI |
| Anti-infective Agent - Miscellaneous Agent Drug | Macrodantin |
| Anti-infective Agent - Miscellaneous Agent Use | Treat acute UTI |
| Anti-infective Agent - Miscellaneous Agent - S/E (2) | peripheral neuropathy & headache |
| Anti-infective Agent - Miscellaneous Agent Intervention (2) | take w/ food, drug discolors urine to a rust brown color |
| Urinary Analgesic Drug | Pyridium (OTC & Dye) |
| Urinary Analgesic Action (2) | Produces local anesthetic affection ureters & bladder, relieves burning pain & urgency associated w/ UTI |
| Urinary Analgesic Interventions (4) | Cause urine to be reddish-orange, if pt develops yellowish ting to skin or scelera which may indicate cumulation therefore stop drug & call DR, stains clothes, not used for long term use - only few days |
| Drug used to treat Overactive Bladder | Ditropan |
| Drug used to treat Overactive Bladder Action (2) | Inhibit contractions & delay urge to void, increasing bladder capacity - fill & empty |
| Drug used to treat Overactive Bladder Uses (2) | Overactive bladder, neurogenic bladder (pts w/ MS or stroke) |
| Drug used to Stimulate Bladder | Urecholine |
| Drug used to Stimulate Bladder Action | Parasympathetic nerve stimulant that causes contraction of muscle in bladder, usually resulting in urination |
| Drug used to stimulate Bladder Use | Non-obstructive urinary retention particularly in post-op pts |