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Heart Failure Drugs

intial and target dosing

QuestionAnswer
Captopril Initial dosing: 6.25 mg TID Target dosing: 50 mg TID
Enalapril Initial dosing: 2.5 mg BID Target dosing: 10 mg BID
Lisinopril Initial dosing: 2.5-5 mg daily Target dosing: 40 mg daily
Candesartan Initial dosing: 4-8 mg daily Target dosing: 32 mg daily
Losartan Initial dosing: 25-50 mg daily Target dosing: 150 mg daily
Valsartan Initial dosing: 20-40 mg BID Target dosing: 80-160 mg BID
Carvedilol Initial dosing: 3.125 mg BID Target dosing: 25 mg BID
Bisoprolol Initial dosing: 1.25 mg daily Target dosing: 10 mg daily
Metoprolol succinate Initial dosing: 12.5-25 mg daily Target dosing: 200 mg daily
Spironolactone Initial dosing: 12.5-25 mg qd Target dosing: 25 mg qd/BID *renal dosing adjustment
Eplerenone Initial dosing: 25 mg qd Target dosing: 50 mg qd *renal dosing adjustment
Furosemide Initial daily dosing: 20-40 mg Max daily dosing: 600 mg duration of action 6-8 hr
Torsemide Initial daily dosing: 10-20 mg Max daily dosing: 200 mg Duration of action: 12-16 hr
Bumetanide Initial daily dosing: 0.5-1 mg Max daily dosing: 10 mg Duration of action 4-6 hr
Created by: Kachmiel