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Ch1 Drug Admin
Route of admin, pros, cons, types
| Question | Answer |
|---|---|
| Pro: safe, self-admin, cheap, no needles | PO |
| Con: Slow, very variable abs, 1st pass metabolism, low predictability | PO |
| Pro: fastest, most accurate blood conc | IV |
| Con: Overdose danger, can't be easily reversed, needs sterile needles and medical technique | IV |
| Pro: Slow, even abs (10~30 mins) | IM |
| Con: needs sterile needles, painful and irritable | IM |
| Pro: Slow, prolonged abs (can take up to 3 years) | SC |
| Con: Variable abs depending on amt of blood flow to area | SC |
| Pro: very fast due to large abs surface area, fast onset, no injection equipment needed | Inhalation |
| Con: irritate nasal passages and lungs due to small solid particles | Inhalation |
| Pro: Localized effect, easy to self-admin | Topical (apply to surface of mucous membranes, not skin) |
| Con: ease of transfer across membranes, can be abs into general circulation | Topical |
| Pro: slow, consistent, controlled, prolonged | Transdermal (across skin) |
| Con: only lipid-sol drugs, can be irritable, abs depends on skin location | Transdermal |
| Pro: highly effective, by-pass BB barrier | Epidural (directly injected into CSF) |
| Con: admin needs trained professional, irreversible, can damage nerves | Epidural |
Created by:
xiaohes
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