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Ch1 Drug Admin

Route of admin, pros, cons, types

QuestionAnswer
Pro: safe, self-admin, cheap, no needles PO
Con: Slow, very variable abs, 1st pass metabolism, low predictability PO
Pro: fastest, most accurate blood conc IV
Con: Overdose danger, can't be easily reversed, needs sterile needles and medical technique IV
Pro: Slow, even abs (10~30 mins) IM
Con: needs sterile needles, painful and irritable IM
Pro: Slow, prolonged abs (can take up to 3 years) SC
Con: Variable abs depending on amt of blood flow to area SC
Pro: very fast due to large abs surface area, fast onset, no injection equipment needed Inhalation
Con: irritate nasal passages and lungs due to small solid particles Inhalation
Pro: Localized effect, easy to self-admin Topical (apply to surface of mucous membranes, not skin)
Con: ease of transfer across membranes, can be abs into general circulation Topical
Pro: slow, consistent, controlled, prolonged Transdermal (across skin)
Con: only lipid-sol drugs, can be irritable, abs depends on skin location Transdermal
Pro: highly effective, by-pass BB barrier Epidural (directly injected into CSF)
Con: admin needs trained professional, irreversible, can damage nerves Epidural
Created by: xiaohes