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Neuro disorders

Stack #14886

s/sx of withdrawal tremors, autonomic imbalance (N/V), delirium tremors (hallucinations, fever, tachycardia, sweating), sz, disordered perceptions, coma
Pathology: Wernicke Encephalopathy deterioration of brain, changes PAG of 3/4th ventricles; mammillary bodies; thalamus; cbllm
Clinical features of Wernicke Enceph oculomotor disturbance (ptosis, B 6th CN palsy, nsytagmus; ataxia with broad based gait; acute dementia
Korsakoff's psychosis selective memory loss, loss of some past memory, signif loss of recent memory, confabulation
RX of WE thiamine, balance electrolytes, nutrition
Polyneuropathy distal to prox; LE> UE; symmetrical, motor, sensory, reflex changes; related to vit B deficiency; slow / incomplete recovery; severe dysesthesias
Cerebellar degeneration typical motor s/sx affecting trunk/LE; degeneration in ant lob/upper part of vermis; develops in alcoholics w/ severe sensitivity to alcohol
Cerbral Cortical Atrophy cortical atrophy w/ dementia, ventricular enlargement
central pontine myelinolysis demyelination of center of pons
clinical features of Central Pontine Myelinolysis severe ataxia, dysarthria, CN palsy, impairment of consciousness
Excitotoxin theory (ALS) overactivity of glutamate sys. Norm AA --> glutamate, attach to Ca channels
Progressive Supranuclear Palsy chronic degenerative dz involving substantia nigra, locus ceruleus, other loss of cells in BG, BS
clinical features of PSP Parkinsonian bradykinesis/rigidity, loss of vertical gaze, increased DTR's, dysphagia/dysarthria, dystonic neck, mild dementia
Created by: 2rabbits