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Pharm Exam 1
material for Exam 1
| Term | Definition |
|---|---|
| First pass | when a drug that goes to the liver before being distributed to the rest of the body |
| Examples of first pass | Enternal (GI), oral or rectal, hepatic artery, or portal vein |
| Examples of non first pass | sublingual, parental, SUBQ, IM, topical, transdermal, or inhalation |
| Ways drugs are excreted | kidney, bowel, lungs, sweat, salivary glands, and mammary glands |
| Agonist | makes a body process happen that would normally happen, just quicker |
| Antagonist | inhibits something the body naturally does from happening |
| Agonist example | Insulin |
| Antagonist example | beta blockers |
| Enzyme interaction | prevents an enzyme reaction from happening in the body |
| Non-specific Interaction | don’t do anything to the persons body, it has another action |
| Non-specific Interaction example | Antibiotics |
| Enzyme interaction example | ACE inhibitors |
| Theraputic index | ratio between a drug's theraputic benefit and it's toxis effects |
| Tolerance | A decreasing response to repeated drug use |
| Dependance | a physiological or psychological need for a drug |
| additive effect | drugs with similar actions work together |
| synergistic effect | combined effect is greater than if used alone |
| antagonist effect | drug effects are less than if given separately |
| idiosyncratic reaction | abnormal response to the drug |
| iatrogenic effects | unintentional treatment |
| teratogenic effects | drugs harmful to fetus |
| mutagenic | drug causes alteration in chromosome structure |
| Carcinogenic | chemicals and drugs that cause cancer |
| C-1 drug | no medical reason to give |
| C-2 drug | highly addictive but have medical use |
| C-3 | counted meds |
| C-4 | counted meds |
| C-5 | controlled but sold OTC |
| Saw Palmetto | diuretic, treatment of BPH |
| Garlic | blood thinner |
| Goldenseal | Antibacterial, antifungal, and antiprotozoal |
| Ginko Biloba | helps boosts memory |
| St. Johns Wart | antidepressant |
| Valerian | sleep aid |
| adverse effects of opioids | sedation, respiratory depression, euphoria, bradycardia |
| meperidine-like drugs | fentanyl, -nil drugs |
| Mathadone-like drugs | methadone |
| morphine-like drugs | heroin, codine, hydrocodone |
| other classification | tramadol |
Created by:
alysha_smith
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