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(a)typical drugs
| Question | Answer |
|---|---|
| what are the atypicals? | chlorpromazine, fluphenazine, haloperidol |
| SE for typicals? | seizure photosensitivity lactation weight gain temp regulation issues SCD |
| which drugs may cause akathisia/motor restlessness, parkinsonism | fluphenazine, haloperidol |
| which drug causes low EPS sx and dystonia pseudoparkinsonism, tachy | chlorpromazine |
| which drugs are high potency | fluphenazine and haloperidol |
| available in depot? | flu and hal |
| which drug is similar to clozapine | zyprexa |
| used for depression maintenance in combo with fluoxitine | zyprexa |
| gives EPS in doses >6mg | risperdal |
| all atypicals share what SE? | NMS |
| which drug causes cataracts | seroquel |
| which atypical has the weakest adverse effects | ziprasidone |
| causes HA/n/v akathesia | abilify |
| causes heavy sedation, dystonia, pseudoparkinsons | clozapine |
| causes insomnia, somnolence, EPS sx | asenapine |
| causes somnolence, akathesia, high glucose, EPS, prolactin | lurasidone |
| which atypicals are approved for maintenance of depression (4) | zyprexa, risperdal, seroquel, abilify |
| influences negative sx, and used in neuroleptics for + sx | ziprasidone |
| used for tx resistant schizophrenia | clozapine |
| used for acute schizo and acute mania with bipolar | asenapine |
| BB for all atypicals | elderly with dementia @increased risk of death and high glucose |
| which drug prolongs QT | ziprasidone |
| prescribers must register | clozapine |
| must get CBC before initiation | clozapine |
| best drug for a new schizo | abilify |
| take with food | ziprasidone and lurasidone |
| "me too" drug that can be used when other neuroleptics d/ced due to EPS | clozapine |
| sublingual | asenapine |
| +signs | delusions hallucinations disorganized speech behavior disturbance |
| - signs | social isolation flat affect poverty of speech anhedonia |