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antidepressant drugs
| Question | Answer |
|---|---|
| may cause weight gain, sex dysfunction, leukopenia, tremor, orthostatic hypotension | phenelzine |
| may cause insomnia, decreased libido, nausea, diarrhea, weight loss, poor appetite (class) | SSRI and SNRI |
| don't use with NSAIDs or other anti-platelets | SSRI |
| take with food | vilazodone |
| don't use with tobacco, warfarin, SSRIs, St Johns Wort, or MAOIs | amitriptylline |
| what drugs cause hypertensive crisis | phenelzine+tyramine or stimulants or Ldopa or pseudoephidrine |
| what causes serotonin syndrome | phenelzine +SSRI or TCA |
| what class has SE of HTN crisis and serotonin syndrome? | MAOI |
| BB cardiac toxicity | amitriptylline |
| may cause anorgasmia, anorexia, impotency | SSRI and SNRI |
| longest duration of action for SSRIs | fluoxetine |
| potent and selective serotonin and NE reuptake inhibitor | pristiq |
| inhibits reuptake of serotonin and NE | amitriptylline |
| deposits into lipid membranes | amitriptylline |
| 5HT1 receptor partial agonist | SSRI |
| inhibits 5HT and NE reuptake, weak reuptake DA | SNRI |
| weak block of DA | buproprion |
| serotonin 2 antagonist | trazodone |
| causes increased cholesterol, proteinuria, high blood pressure | pristiq |
| causes sedation, weight gain, neutropenia | mirtazapine |
| X in hx of seizures, bulemia | buproprion |
| causes priapism | trazodone |
| decreases NE release and increases serotonin synthesis | lithium |
| histone deacetylase inhibitor | VPA |
| sodium channel blocker | lamotrigine |
| tricyclic that limits electrical action | carbamazepine |
| used for acute mania, acute depression, bipolar maintenance | lithium |
| used for acute mania, mixed, maintenance | VPA |
| long term maintenance of adults with bipolar | lamotrigine |
| used for acute and mixed mania | carbamazepine |
| may cause tremor, hair loss, hepatotox | VPA |
| wt gain, polydipsia, polyuria, hypothyroid, arrythmias, ataxia | lithium |
| causes rash if rushed | lamotrigine |
| causes SJS, lots skins stuffs, anti-diuretic, ataxia, diplopia | carbamazepine |
| may become toxic if pt is dehydrated | lithium |
| don't use with diuretics, NSAIDs, ACEi, ARBs | lithium |
| don't use with HIV meds | VPA |
| inhibits CYP450, so dont use with warfarin | VPA and vilazodone |
| what are the mood stabilizers? | lithium, VPA, lamotrigine, carbamazepine |
| what is the indication for SNRIs? | severe depression when increased drive is desired |
| are tricyclics or SSRI more potent for depression? | tricyclics |
| do tricyclics or SSRIs have more SE? | tricyclics |
| which drug is ok to breastfeed? | amitriptylline |
| what should you monitor with pristiq? | BP and urine analysis |
| all AD cause weight gain except.... | SSRI, SNRI, buproprion |
| most teratogenic? | lithium and VPA and carbamazepine |
Created by:
duanea00
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