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Cirrhosis Drugs
Question | Answer |
---|---|
non-selective ß-blocker causes splanchnic vasoconstriction | nadolol |
decreases intestinal NH3 by acting against urease producing bacteria | neomycin sulfate |
somatostatin analog; inhibits serotonin, gastrin, insulin, glucagon and alters mesenteric/sphlanchnic blood flow promoting hemostasis | octreotide |
inhibits binding of aldosterone to receptor | spironolactone |
inhibits sodium-potassium symport in ascending limb | furosemide |
used in cirrhosis induced hepatic encephalopathy | neomycin sulfate |
used for bleeding esophageal varicies | octreotide and nadolol |
used for cirrhosis induced edema | spironolactone and furosemide |
causes nephro and ototoxicity | neomycin sulfate |
causes gynecomastia | spironolactone |
monitor B12 levels, cholelithiasis, hypothyroidism, anemia | octreotide |
avoid NSAIDs | spironolactone and furosemide |
aides in hydrolysis of fats, proteins and starches | pancrelipase |
interacts with iron salts, iron, multivitamins | pancrelipase |
monitor growth and development | pancrelipase |
titrate "low and go slow" | pancrelipase |
how do you monitor the effectivity of neomycin sulfate? | clinical improvement |
used after removal of >5L paracentesis | albumin 25% |
how long for diuretics to reach "steady state"? and how often should you adjust dose? | 3-5 days |
don't use with DM or renal impairment | octreotide |
which 2 cirrhosis drugs are pricy? | octreotide and albumin 25% |