click below
click below
Normal Size Small Size show me how
Cirrhosis Drugs
| Question | Answer |
|---|---|
| non-selective ß-blocker causes splanchnic vasoconstriction | nadolol |
| decreases intestinal NH3 by acting against urease producing bacteria | neomycin sulfate |
| somatostatin analog; inhibits serotonin, gastrin, insulin, glucagon and alters mesenteric/sphlanchnic blood flow promoting hemostasis | octreotide |
| inhibits binding of aldosterone to receptor | spironolactone |
| inhibits sodium-potassium symport in ascending limb | furosemide |
| used in cirrhosis induced hepatic encephalopathy | neomycin sulfate |
| used for bleeding esophageal varicies | octreotide and nadolol |
| used for cirrhosis induced edema | spironolactone and furosemide |
| causes nephro and ototoxicity | neomycin sulfate |
| causes gynecomastia | spironolactone |
| monitor B12 levels, cholelithiasis, hypothyroidism, anemia | octreotide |
| avoid NSAIDs | spironolactone and furosemide |
| aides in hydrolysis of fats, proteins and starches | pancrelipase |
| interacts with iron salts, iron, multivitamins | pancrelipase |
| monitor growth and development | pancrelipase |
| titrate "low and go slow" | pancrelipase |
| how do you monitor the effectivity of neomycin sulfate? | clinical improvement |
| used after removal of >5L paracentesis | albumin 25% |
| how long for diuretics to reach "steady state"? and how often should you adjust dose? | 3-5 days |
| don't use with DM or renal impairment | octreotide |
| which 2 cirrhosis drugs are pricy? | octreotide and albumin 25% |