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Integrase Inhibitor
Antiretroviral
Question | Answer |
---|---|
Raltegravir | integrase inhibitor, prevents integration of RT viral DNA into host genome |
Integrase | viral enzyme for replication of both HIV 1 and 2 |
Integrase inhibitors | bind to integrase to inhibit strand transfer (third and final step of provirus integration) thus interfering with the integration of reverse-transcribed HIV DNA into the chromosomes of host cell |