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NRTI

Nucleoside/Nucleotide Antiretroviral Agents

TermDefinition
NRTI (nucleoside/nucleotide) inhibits HIV-1 reverse transcriptase (RT); requires activation via phosphorylation by cellular enzymes to the triphosphate form; mitochondrial toxicity-inhibit mitochondrial DNA polymerase gamma
Abacavir, Tenofer, Zidovudine, Didanosine, Lamivudine, Zalcitabine, Emtricitabine, Stavdine NRTI, Renal excretion (kidneys)
Abacavir NRTI, BLACK BOX: FATAL HYPERSENSITVITY RXN
Created by: cburrows
Popular Pharmacology sets

 

 



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