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Term FCC week 3
Terminology
| Term | Definition |
|---|---|
| absorption | The process of drug movement into the systemic circulation. |
| ADR | adverse drug reaction |
| adverse effects | Harmful effects. |
| affinity | Attractive force. |
| agonist | A drug that binds to a receptor and produces a stimulatory response that is similar to what an endogenous substance (such as a hormone) would have done if it were bound to the receptor. |
| alteration | How the body absorbs, distributes, metabolizes, or excretes a drug. |
| anaphylactic shock | Sudden and severe allergic reaction that may be life threatening. |
| antagonist | A drug or another agent that blocks or antagonizes the effects of another substance or function. |
| bioavailability | The extent to which a drug or other substance is taken up by a specific tissue or organ after administration. |
| biotransformation | The process of conversion of drugs. |
| conjugation | The combination of substances with gulcuronic or sulfuric acid, terminating biologic activity and making them ready for excretion. |
| contraindication | A reason that makes it inadvisable to prescribe a particular drug. |
| cumulative effect | Poor metabolism or excretion of a drug leads to a build-up of the drug in the body. |
| dissolution | The process of dissolving. |
| distribution | The passage of an agent through blood or lymph to various body sites |
| dose-effect relationship | The relationship between the dose of a drug (or other agent) that produces therapeutic effects and the potency of the effects on the person. Aka - dose-response relationship. |
| excretion | The last stage of pharmacokinetics that removes drugs from the system. |
| first-pass effect | After the drug is in the liver, it is partly metabolized before being sent to the body, where systemic effects occur. |
| half-life | (t ½) The time taken for the blood or plasma concentration of the drug to decrease from full to one-half (50%). |
| hydrolysis | The cleaving of a compound into simpler compounds with the uptake of the hydrogen and hydroxide parts of a water molecule |
| idiosyncratic | Something peculiar to an individual |
| medicine (medication) | Drugs mixed in a formulation with other ingredients to improve the stability, taste, or physical form to allow appropriate administration of the active drug. |
| metabolism | The sum of chemical and physical changes in the tissues, consisting of anabolism and catabolism. |
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