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Term FCC week 3


absorption The process of drug movement into the systemic circulation.
ADR adverse drug reaction
adverse effects Harmful effects.
affinity Attractive force.
agonist A drug that binds to a receptor and produces a stimulatory response that is similar to what an endogenous substance (such as a hormone) would have done if it were bound to the receptor.
alteration How the body absorbs, distributes, metabolizes, or excretes a drug.
anaphylactic shock Sudden and severe allergic reaction that may be life threatening.
antagonist A drug or another agent that blocks or antagonizes the effects of another substance or function.
bioavailability The extent to which a drug or other substance is taken up by a specific tissue or organ after administration.
biotransformation The process of conversion of drugs.
conjugation The combination of substances with gulcuronic or sulfuric acid, terminating biologic activity and making them ready for excretion.
contraindication A reason that makes it inadvisable to prescribe a particular drug.
cumulative effect Poor metabolism or excretion of a drug leads to a build-up of the drug in the body.
dissolution The process of dissolving.
distribution The passage of an agent through blood or lymph to various body sites
dose-effect relationship The relationship between the dose of a drug (or other agent) that produces therapeutic effects and the potency of the effects on the person. Aka - dose-response relationship.
excretion The last stage of pharmacokinetics that removes drugs from the system.
first-pass effect After the drug is in the liver, it is partly metabolized before being sent to the body, where systemic effects occur.
half-life (t ½) The time taken for the blood or plasma concentration of the drug to decrease from full to one-half (50%).
hydrolysis The cleaving of a compound into simpler compounds with the uptake of the hydrogen and hydroxide parts of a water molecule
idiosyncratic Something peculiar to an individual
medicine (medication) Drugs mixed in a formulation with other ingredients to improve the stability, taste, or physical form to allow appropriate administration of the active drug.
metabolism The sum of chemical and physical changes in the tissues, consisting of anabolism and catabolism.
Created by: 1662466248



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