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Anti-hypertensive drugs

Common diuretics Thiazide, Loop diuretics, K+ Sparing
Example of Thiazide Hydrochlorothiazide
Example of loop diuretic Furosemide
Example of K+ Sparing Spironolactone
ACE Inhibitors Captopril, lisinopril, ramipril, enalopril
Angiotensin receptor blocker Losartan, Valsartan, Telmisartan
Direct Renin Inhibitor Alliskiren
Beta-adrenergic blocker [Non-selective] Propranolol, pindolol, labetolol
Beta-adrenergic blocker [Cardioselective] Metaprolol, esmolol, betaxolol
Beta-Alpha adrenergic blocker Labetolol, Carvedilol
Selective Aplha-1 adrenergic blocker Prazosin, Doxazosin
Agents that prevent adrenergic transmission Reserpine, Guanadrel
Centrally Acting Clonidine, Methyldopa
Calcium channel blockers Diltiazem, Verapamil, Felodipine
Potassium channel activator Nicorandil, Diazoxide
Vasodilators [Arterial] Hydralazine
Vasodilator [Arterio-venular] Potassium Nitroprusside
Indication for ACEI/ARB Acute Myocardial Infarction, Hypertension, Heart Failure, Cardiovascular protection Nephropathy
Adverse Effects of ACEI/ARB Hypotention, Renal failure, Cough, Hyperkalemia,Skin reaction
Contraindication of ACEI/ARB Pregnancy, Pre-existing hypotension, hyperkalemia, bilateral renal artery stenosis
Beta-1 adrenergic receptor Located in the heart
Beta-2 adrenergic receptor Located in smooth muscles of bronchioles, arterioles, and visceral organs
Beta-3 adrenergic receptor Located in adipose tissue,vascular endothelium
Alpha-2 adrenergic receptor Located in presynaptic nerve terminals
Alpha-1 adrenergic receptor Located in post synaptic of effector cells
Created by: any0ne_



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