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Pharmacy Final 1/3

NUR 117 Pharmacology Final Set 1 out of 3

Warfarin (Coumadin) Class Anticoag
Warfarin (Coumadin) Act Prevents clotting
Warfarin (Coumadin) Use DVT , PE, PVD
Warfarin (Coumadin) SE Bleeding
Warfarin (Coumadin) NI PT/INR, Antidote Vit K
protamine Class Antidote
protamine Act Reverses heparin
protamine Use Heparin coagulopathy
protamine SE none given
protamine NI none given
Vitamin K Class Vitamin
Vitamin K Act NZ cofactor, clotting NZ cofactor, warfarin antidote
Vitamin K Use Warfarin coagulopathy
Vitamin K SE none given
Vitamin K NI none given
Atenolol (Tenormin) Class Sympatholytic, B-blocker
Atenolol (Tenormin) Act B blockade
Atenolol (Tenormin) Use Hypertension, dysrhythmia
Atenolol (Tenormin) SE HoTN, bradycardia, ↓libito & impotence
Atenolol (Tenormin) NI monitor VS
Digoxin (Lanoxin) Class Cardiac glycoside
Digoxin (Lanoxin) Act Increases heart squeeze
Digoxin (Lanoxin) Use Increases heart squeeze
Digoxin (Lanoxin) SE dysrhythmias
Digoxin (Lanoxin) NI Monitor dig levels (therapeutic 0.5-2). Monitor K, Apical for 1 min, Antidote Dig Immune Fab (Digibind)
Simvastatin (Zocor) Class Anticholesterol, antilipid
Simvastatin (Zocor) Act Blocks HMG CoA reductase
Simvastatin (Zocor) Use Liver toxicity
Simvastatin (Zocor) SE Hypercholesterolemia
Simvastatin (Zocor) NI Monitor cholesterol. Monitor LFTs
Acetaminophen (Tylenol) Class Analgesic, antipyretic
Acetaminophen (Tylenol) Act MOA unknown.
Acetaminophen (Tylenol) Use Mild-mod pain, fever
Acetaminophen (Tylenol) SE Liver toxicity in overdose
Acetaminophen (Tylenol) NI Avoid w/ liver Dz. Max dose 1g/ds. 4g/24h
Ezetimibe (Zetia) Class Anticholesterol, antilipid
Ezetimibe (Zetia) Act prevents cholesterol reabsorption. this drug is NOT a statin
Ezetimibe (Zetia) Use hypercholesterolema
Ezetimibe (Zetia) SE none given
Ezetimibe (Zetia) NI none given
Metoprolol (Lopressor) Class Sympatholytic, B-blocker
Metoprolol (Lopressor) Act B blockade
Metoprolol (Lopressor) Use Hypertension, dysrhythmia
Metoprolol (Lopressor) SE HoTN, bradycardia
Metoprolol (Lopressor) NI Monitor vitals
Promethazine (Phenergan) Class Phenothiazine Antiemetic
Promethazine (Phenergan) Act ↓nausea, alters dopamine, dopamine antagonist
Promethazine (Phenergan) Use ↓nausea, alters dopamine, dopamine antagonist
Promethazine (Phenergan) SE EPS, tranquilizing effects, NMS, sedation, anticholinergic effects, HoTN, urine color, agranulycytosis
Promethazine (Phenergan) NI monitor vitals, monitor CBC
Heparin Class Anticoagulant
Heparin Act Inhibits clotting
Heparin Use MI, DVT, PE, PVD
Heparin SE Bleeding, thrombocytopenia (HIT)
Heparin NI Follow PTT, antidote protamine
Morphine (morphine sulfate) Class Opiod analgesic
Morphine (morphine sulfate) Act Binds to opiod receptors
Morphine (morphine sulfate) Use Mod-Severe pain
Morphine (morphine sulfate) SE ↓RR, ↓BP, constipation Hives (morphine)
Morphine (morphine sulfate) NI any route
Nedocromil (Tilade) Class Mast cell stablizer (like cromolyn [Intal])
Nedocromil (Tilade) Act Inhibits mast cell degranuation
Nedocromil (Tilade) Use allergies
Nedocromil (Tilade) SE none given
Nedocromil (Tilade) NI none given
Levalbuterol (Xopenex) Class Sympathomimetic B2 agonist
Levalbuterol (Xopenex) Act Bronchodilator
Levalbuterol (Xopenex) Use Asthma, COPD, emphysema
Levalbuterol (Xopenex) SE ↑HR, jittery, transient ↓K, chest pain, dysrhythmia, interaction w/ MAOI
Levalbuterol (Xopenex) NI Rinse & spit
Rivastigmine (Exelon) Class Cholinergic
Rivastigmine (Exelon) Act Increases acetylcholine
Rivastigmine (Exelon) Use Alzheimer’s
Rivastigmine (Exelon) SE SLUDGE, wt loss
Rivastigmine (Exelon) NI May use w/ antipsychotic
Benztropine (Cogentin) Class Anticholinergic / antihistamine
Benztropine (Cogentin) Act Blocks H1, blocks Ach receptor site
Benztropine (Cogentin) Use EPS side effects
Benztropine (Cogentin) SE ↑HR, dry, mydriasis
Benztropine (Cogentin) NI monitor VS
Tacrine (Cognex) Class Cholinergic
Tacrine (Cognex) Use Alzheimer's dementia
Tacrine (Cognex) Act increases acetylcholine
Tacrine (Cognex) SE Wt loss, liver tox, SLUDGE
Tacrine (Cognex) NI monitor LFTs
Galantamine (Razadyne) Class Cholinergic
Galantamine (Razadyne) Act Cholinergic
Galantamine (Razadyne) Use Alzheimer's dementia
Galantamine (Razadyne) SE Wt loss, liver tox, SLUDGE
Galantamine (Razadyne) NI monitor LFTs
Primidone (Mysoline) Class Antiseizure drug, barbiturate
Primidone (Mysoline) Act Prodrug to phenobarbital
Primidone (Mysoline) Use Seizures
Primidone (Mysoline) SE ↓CNS, blood dyscracias, folate deficiency
Primidone (Mysoline) NI Follow phenobarb level, CBC, folate, & diet
Cyclophosphamide (Cytoxan) Class CA drug, alkalizing agent
Cyclophosphamide (Cytoxan) Act Interferes with DNA in dividing CA cells
Cyclophosphamide (Cytoxan) Use BRCA, ovarian, lymphoma, hemorrhagic cystitis
Cyclophosphamide (Cytoxan) SE Anemia, Neutropenia, Thrombocytopenia (Pancytopenia all 3), N/V/D, allopecia
Cyclophosphamide (Cytoxan) NI Give 7-10d, peak 1-2d, potentiates anticoag & insulin, immune boosters may antagonize drug.
Epoeitin alfa (Epogen) Class CA adjuvant
Epoeitin alfa (Epogen) Act Promotes erythropoesis. Promotes bone marrow
Epoeitin alfa (Epogen) Use Anemia (bio response modifier)
Epoeitin alfa (Epogen) SE HTN, injection site reaction, dyspnea, rash
Epoeitin alfa (Epogen) NI Do not use for leukemia/lymphoma, chilled & must be warmed
Fexofenadine (Allegra) Class Antihistamine
Fexofenadine (Allegra) Act Blocks H1
Fexofenadine (Allegra) Use Allergies, colds
Fexofenadine (Allegra) SE Drowsiness, dry, anticholergic , HoTN, urinary retention
Fexofenadine (Allegra) NI Drink fluids
Terbutaline (Brethaire) Class Sympathomimetic B2 agonist
Terbutaline (Brethaire) Act Bronchodilator
Terbutaline (Brethaire) Use Asthma, COPD, emphysema
Terbutaline (Brethaire) SE ↑HR, jittery, transient ↓K, chest pain, dysrhythmias
Terbutaline (Brethaire) NI Rinse & spit, interaction w/ MAO Inhibitors
Budesonide (Pulmicort) Class Nasal corticosteroid
Budesonide (Pulmicort) Act Inhibits inflammation
Budesonide (Pulmicort) Use Allergic rhinitis
Budesonide (Pulmicort) SE Dry nose, irritation
Created by: mojoshare
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