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pharmaceutically useful bacteria and their pharmaceutical relevance

OrganismPharmaceutical relevance
Actinomyces spp. Antibiotic production
Bacillus atrophaeus Validate and monitor dry heat and ethylene oxide sterilization processes
Bacillus pumilus Validate and monitor radiation sterilization processes
Bordetella pertussis Vaccine against whooping cough Causative agent of whooping cough
Brevundimonas diminuta 0.22-µm filter challenge test
Clostridium sporogenes Confirm anaerobic growth conditions
Clostridium tetani Vaccine against tetanus Causative agent of tetanus
Corynebacterium diphtheriae Vaccine against diphtheria Causative agent of diphtheria
Escherichia coli Kelsey-Sykes disinfectant capacity test Preservative limit test Food poisoning, severe enteritis
Geobacillus stearothermophilus Validate and monitor moist heat sterilization processes
Haemophilus influenzae type b Vaccine against Hib infections Causative agent of infantile meningitis and chronic bronchitis
Leuconostoc mesenteroides Dextran production
Neisseria meningitidis Vaccine against meningitis C
Pseudomonas aeruginosa Alginate production Kelsey-Sykes disinfectant capacity test General environmental contaminant Quintessential opportunist pathogen High resistance to antibiotics and biocides Biofilm-former
Proteus vulgaris Kelsey-Sykes disinfectant capacity test
Salmonella enterica serovar Typhi Chick Martin/Rideal Walker disinfectant coefficient test
Staphylococcus aureus Kelsey-Sykes disinfectant capacity test Preservative limit test Skin contaminant Food poisoning Toxic shock syndrome Pyogenic infections
Bacteroides fragilis Wound infections
Campylobacter jejuni Severe enteritis
Legionella pneumophila Causative agent of Legionnaire’s disease
Mycobacterium tuberculosis Causative agent of tuberculosis Disinfectant resistance Intracellular pathogen
Salmonella spp. Varying degrees of food poisoning, typhoid fever
Staphylococcus epidermidis Implanted medical device/prosthetic device contaminant Biofilm-former
Streptococcus spp. Causative agents of tonsilitis and scarlet fever
Created by: purple_amethyst