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Pharmacology
CARDIOVASCULAR AND RENAL SYSTEMS Hematopoietic Drugs
Question | Answer |
---|---|
Hematopoietic Drugs are used to treat___ deficiencies? | Nutritional deficiences. Iron deficiency anemia |
Oral iron preparations available as ferrous___ Should never be exchanged for one another. | salts. |
iron dextran, iron sucrose, ferric gluconate are ___ preparations | Parenteral |
nausea, vomiting, diarrhea,constipation, stomach cramps/pain. Excess intake leads to iron toxicity are the adverse drug reactions for ____. | Hematopoietic drugs |
Folic Acid deficiency anemia Ingestion required for ___ of DNA & RNA; essential for normal erythropoiesis | production |
What should not be used until underlying cause & type of anemia is determined. | Folic Acid |
What causes signs of folic acid deficiency? | BC pills,corticosteroids, sulfonamides all cause signs of folic acid deficiency. |
Folic acid can lower ____levels | phenytoin serum |
Cyanocobalamin deficiency anemia; ___ drugs are to treat ____ anemia and ___ anemias. | pernicious anemia and megloblastic anemias. |
What forms of hematopoietic drugs are given when treating cyanocobalamin deficiency anemia? | Given PO or intranasally, IM |
What are two Erythropoietic Drugs? | Epoetin alfa(Epogen,Procrit) and darbepoetin(Aranesp): |
Epoetin alfa(Epogen,Procrit) and darbepoetin(Aranesp stimulate _____ production of ___ | stimulates bone marrow production of RBCs |
Erythropoietic drugs are used to ___ or ____ associated with chronic renal failure and myelosuppression chemotherapy. | prevent or treat anemia |
Taking Eryhtopoietic drugs are associated with increased cardiovascular complications and tumor progression if used to achieve __________ levels. | Associated with increased cardiovascular complications and tumor progression if used to achieved normal hemoglobin levels |
Colony Stimulating Factors: Filgrastim(Neupogen) is used to stimulate _____ production by bone marrow following bone marrow transplant or chemotherapy induced neutropenia | blood cell |
____is both a hematopoietic drug and platelet enhancer | Oprelvekin(Neumega): |
Oprelvekin(Neumega): is both ____ and _____ | both hematopoietic drug & interleukin |
Oprelvekin(Neumega): is indicated for prevention of chemotherapy induce severe _____and avoidance of need for platelet transfusion in adults. | thrombocytopenia |