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Pharmacology
CARDIOVASCULAR & RENAL SYSTEMS Coagulation Modifying Agents
| Question | Answer |
|---|---|
| Coagulation Modifying Agents treat ___of the _____ system | Treat disorders of the blood clotting system |
| What are these: Thrombus Embolus Fibrin | 1. Thrombus: Blood clot final product of the blood coagulation 2. Embolusany detached, traveling intravascular mass (solid, liquid, or gaseous) carried by circulation, 3. Fibrin is a fibrous, non-globular protein involved in clotting of blood |
| What are the different types of Coagulation Modifying Drugs? | 1.Anticoagulants: Parenteral 2. Anticoagulants: Oral 3. Antiplatelets 4. Thrombolytics 5. Antifibrinolytics 6. Replacement therapy for hemophilia |
| Anticoagulants: Parenteral inhibit ____ formation | clot formation |
| Anticoagulants: Parenteral binds to ______ to turn off activating factors which make a ___ | anti-thrombin III; clot |
| Heparin, enoxaparin (Lovenox) are examples of which type of drugs? | Anticoagulants: Parenteral |
| What is the antidote for Heparin ( anticoagulant?) | Protamine Sulfate |
| What is the side effect of anticoagulants ( parenteral) | bleeding |
| Anticoagulants: Oral inihibit ___ formation | Clot |
| Anticoagulants ( Oral) inhibit ______ clotting factors (_______?) | Vitamin K clotting factors (II, VII, IX, X) |
| warfarin (Coumadin) is an example of an | Anticoagulant (Oral) |
| What is the anti doe of warfarin? | Vitamin K |
| What is the side effect of Warfarin ( anticoagulant?) | bleeding |
| Antiplatelets work to ___ the platelet _____ to site of BW injury | prevent; platelet adhesion ( (keep platelets from clumping together) |
| What is the MOA of anti platelets? | many affect the cyclooxygenase pathway |
| aspirin & clopidogrel (Plavix) is a common medication of the ___ class. | Antiplatelet |
| What is the side effect of anti platelets? | bleeding |
| Thrombolytics convert plasminogen to ___, ___ or ___ clots to restore blood supply to damaged ____. | plasmin; breakdown, or lyse; damaged myocardium |
| streptokinase (SK), Streptase is a common medication of ____. | Thrombolytics |
| What is the side effect of Thrombolytics? | Bleeding |
| what is an example of a Hemostatic Agent? | Antifibrinolytics |
| Antifibrinolytics promote ___ formation by inhibiting the ____ of _____ | clot formation; lysis (breakdown) ; fibrin |
| Aminocaproic Acid ( Amicar) is an example of a common drug for _____ | Antifyinolytics |
| What is the side effect of Antifyinolytics? | Blood Clot (thrombus) |
| What deficiency of factor ____,___ or ___ lead to replacement therapy for hemophilia? | factor VIII, IX or XI |
| What is a drug used for replacement therapy for hemophilia? | Desmopressin/DDAVP |
| The following are nursing considerations for? Monitor lab tests: eg., Hgb, HCT, PT, aPTT, INR (p 432) Assess ALL ORIFICES for bleeding; report abnormal bleeding Assess for easy bruising Use soft bristle toothbrush | ______ Maybe (Hemostatic) Agents |
| Notify MD if client develops neurological dysfunction Do not eat foods high in vitamin K Teach patient safety while taking medication at home Take oral anticoagulants at the same time every day to maintain steady blood levels | ______ Maybe Hemostatic Agents |
| Do not double missed doses is a nursing consideration for | ______ Maybe Hemostatic Agents |
Created by:
jwhite223
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