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Pharmacology

CARDIOVASCULAR & RENAL SYSTEMS Coagulation Modifying Agents

QuestionAnswer
Coagulation Modifying Agents treat ___of the _____ system Treat disorders of the blood clotting system
What are these: Thrombus Embolus Fibrin 
 1. Thrombus: Blood clot final product of the blood coagulation 2. Embolusany detached, traveling intravascular mass (solid, liquid, or gaseous) carried by circulation, 3. Fibrin is a fibrous, non-globular protein involved in clotting of blood
What are the different types of Coagulation Modifying Drugs? 1.Anticoagulants: Parenteral 2. Anticoagulants: Oral 3. Antiplatelets 4. Thrombolytics 5. Antifibrinolytics 6. Replacement therapy for hemophilia
Anticoagulants: Parenteral inhibit ____ formation clot formation
Anticoagulants: Parenteral binds to ______ to turn off activating factors which make a ___ anti-thrombin III; clot
Heparin, enoxaparin (Lovenox) are examples of which type of drugs? Anticoagulants: Parenteral
What is the antidote for Heparin ( anticoagulant?) Protamine Sulfate
What is the side effect of anticoagulants ( parenteral) bleeding
Anticoagulants: Oral inihibit ___ formation Clot
Anticoagulants ( Oral) inhibit ______ clotting factors (_______?) Vitamin K clotting factors (II, VII, IX, X)
warfarin (Coumadin) is an example of an Anticoagulant (Oral)
What is the anti doe of warfarin? Vitamin K
What is the side effect of Warfarin ( anticoagulant?) bleeding
Antiplatelets work to ___ the platelet _____ to site of BW injury prevent; platelet adhesion ( (keep platelets from clumping together)
What is the MOA of anti platelets? many affect the cyclooxygenase pathway
aspirin & clopidogrel (Plavix) is a common medication of the ___ class. Antiplatelet
What is the side effect of anti platelets? bleeding
Thrombolytics convert plasminogen to ___, ___ or ___ clots to restore blood supply to damaged ____. plasmin; breakdown, or lyse; damaged myocardium
streptokinase (SK), Streptase is a common medication of ____. Thrombolytics
What is the side effect of Thrombolytics? Bleeding
what is an example of a Hemostatic Agent? Antifibrinolytics
Antifibrinolytics promote ___ formation by inhibiting the ____ of _____ clot formation; lysis (breakdown) ; fibrin
Aminocaproic Acid ( Amicar) is an example of a common drug for _____ Antifyinolytics
What is the side effect of Antifyinolytics? Blood Clot (thrombus)
What deficiency of factor ____,___ or ___ lead to replacement therapy for hemophilia? factor VIII, IX or XI
What is a drug used for replacement therapy for hemophilia? Desmopressin/DDAVP
The following are nursing considerations for? Monitor lab tests: eg., Hgb, HCT, PT, aPTT, INR (p 432) Assess ALL ORIFICES for bleeding; report abnormal bleeding Assess for easy bruising Use soft bristle toothbrush ______ Maybe (Hemostatic) Agents
Notify MD if client develops neurological dysfunction Do not eat foods high in vitamin K Teach patient safety while taking medication at home Take oral anticoagulants at the same time every day to maintain steady blood levels ______ Maybe Hemostatic Agents
Do not double missed doses is a nursing consideration for ______ Maybe Hemostatic Agents
Created by: jwhite223
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