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Pharmacology
CARDIOVASCULAR & RENAL SYSTEMS Diuretic Agents
| Question | Answer |
|---|---|
| Diuretic Agents, treat_____, ____, & _____. | Treat Edema, Congestive Heart Failure, and Hypertension |
| What are the four functions of Renal System? | 1. Formation and Excretion of Urine 2. Regulates fluid and electrolyte balance 3. Regulates blood pressure (renin enzyme) 4. Stimulates production of RBCs in bone marrow (erythropoietin hormone) |
| Diuretics inhibit _____ reabsorption | Inhibit Na reabsorption |
| Diuretics cause volume _____. | depletion |
| Diuretics cause _____ of peripheral arterioles | Vasodilation |
| Diuretics are ___ in combination therpay | Prescribed in combination therapy |
| Diuretics Potentiate the hypotensive activity of the _____ agents | nondiuretic antihypertensive |
| Diuretics have _____ incidence of ____ effects. | Low incidence of adverse effects |
| What are the two most common diuretic medications? | 1. Furosemide (Lasix) 2. Hydrochlorothiazide (HydroDIURIL) |
| Regardin diuretic agents the MOA and types of diuretics depend on _____. | depend on anatomical site. |
| Re: Loop diuretic; it inhibits ___ reabsorption in ____. by direct action on ____ Loop of Henle | NA;ascending |
| Common medication for a loop diuretic is ______ | Furosemide (Lasix) |
| What is the onset time for Furosemide (Lasix)? | 30-45 minutes |
| Hhyponatremia, hypokalemia are side effects of _____? | Furosemide (Lasix) |
| Potassium Sparing Diuretic inhibit ___ reabsorption in the _____ ducts and distal convoluted tubules | NA |
| Spironolactone (Aldactone) is a common medicine for a ______ diuretic. | Potassium Sparing Diuretic |
| hyponatremia, hyperkalemia are side effects of which are similar to _____ (lasix) | Spironolactone (Aldactone; Furosemide |
| Osmotic Diuretic Causes a shift in _____to move into the renal tubules from the surrounding tissue | in fluid |
| Mannitol (Osmitrol) is a common drug for a ____ | Osmotic Diuretic |
| Mannitol (Osmitrol) Produces greatest amount of____output | urine |
| Circulatory overload is a side effect of_____ which is an ____Diuretic | Mannitol (Osmitrol);Osmotic |
| Thiazide Diuretic inhibits ___,___, & ____ resorption in the distal convoluted tubule | Na, K & Cl resorption |
| hydrochlorothiazide (HydroDIURIL) is a common medicine for_______. | Thiazide Diuretic |
| hydrochlorothiazide (HydroDIURIL) is the most common drug for ____Diuretic is common because its _____. | Thiazide ; low in cost |
| ypokalemia, hypercalcemia, hyperlipidemia, hyperglycemia & hyperuricemia are the side effects of _____. | hydrochlorothiazide (HydroDIURIL) |
| Thiazide diuretics are considered to be ____ | “potassium-wasting” |
| When Thiazide diuretics are used ______is the electrolyte imbalance most often seen | Hypokalemia |
| Orthostatic hypotension Hypokalemia (exception: K+ sparing diuretics such as spironolactone) Hyponatremia are common side effects for___? | Of diuretic drug therapy: |
| Monitor renal function & urine output Daily weight Postural blood pressure checks; are nursing consideration for | diuretic drug therapy |
| Client change positions slowly & rise slowly Monitor HR & rhythm Assess skin & mucous membranes Monitor serum Na and K+ levels Increased excretion of all medications Administer in the morning or early afternoon; are nursing consideration for | diuretic drug therapy |
| Adrenergic Drugs Exert their action at ___ sites | different |
| Clonidine, guanfacine, methyldopa stimulate a-2 adrenergic receptors in the ___ | brain |
| Clonidine, guanfacine, methyldopa are ____ acting | Central action ( in the brain) |
| Doxazosin, prazosin, terazosin block ___ receptors, dilating arteries & veins to reduce PVR & thus reduce ___. | a-1 adrenergic; BP |
| Doxazosin, prazosin, terazosin are ____ action | Peripheral action (at the heart & blood vessels) |
| Propranolol & atenolo block ___ receptors and reduce ____ secretion | block b-1 receptors & reduce renin secretion |
| (labetalol, carvedilol (Coreg)) are ____which reduce HR and ____vessels | Dual action a1 & b receptor blockers; dilate |
Created by:
jwhite223
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