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Pharmacology

CARDIOVASCULAR & RENAL SYSTEMS Diuretic Agents

QuestionAnswer
Diuretic Agents, treat_____, ____, & _____. Treat Edema, Congestive Heart Failure, and Hypertension
What are the four functions of Renal System? 1. Formation and Excretion of Urine 2. Regulates fluid and electrolyte balance 3. Regulates blood pressure (renin enzyme) 4. Stimulates production of RBCs in bone marrow (erythropoietin hormone)
Diuretics inhibit _____ reabsorption Inhibit Na reabsorption
Diuretics cause volume _____. depletion
Diuretics cause _____ of peripheral arterioles Vasodilation
Diuretics are ___ in combination therpay Prescribed in combination therapy
Diuretics Potentiate the hypotensive activity of the _____ agents nondiuretic antihypertensive
Diuretics have _____ incidence of ____ effects. Low incidence of adverse effects
What are the two most common diuretic medications? 1. Furosemide (Lasix) 2. 
Hydrochlorothiazide (HydroDIURIL)
Regardin diuretic agents the MOA and types of diuretics depend on _____. depend on anatomical site.
Re: Loop diuretic; it inhibits ___ reabsorption in ____. by direct action on ____ Loop of Henle NA;ascending
Common medication for a loop diuretic is ______ Furosemide (Lasix)
What is the onset time for Furosemide (Lasix)? 30-45 minutes
Hhyponatremia, hypokalemia are side effects of _____? Furosemide (Lasix)
Potassium Sparing Diuretic inhibit ___ reabsorption in the _____ ducts and distal convoluted tubules NA
Spironolactone (Aldactone) is a common medicine for a ______ diuretic. Potassium Sparing Diuretic
hyponatremia, hyperkalemia are side effects of which are similar to _____ (lasix) Spironolactone (Aldactone; Furosemide
Osmotic Diuretic Causes a shift in _____to move into the renal tubules from the surrounding tissue in fluid
Mannitol (Osmitrol) is a common drug for a ____ Osmotic Diuretic
Mannitol (Osmitrol) Produces greatest amount of____output urine
Circulatory overload is a side effect of_____ which is an ____Diuretic Mannitol (Osmitrol);Osmotic
Thiazide Diuretic inhibits ___,___, & ____ resorption in the distal convoluted tubule Na, K & Cl resorption
hydrochlorothiazide (HydroDIURIL) is a common medicine for_______. Thiazide Diuretic
hydrochlorothiazide (HydroDIURIL) is the most common drug for ____Diuretic is common because its _____. Thiazide ; low in cost
ypokalemia, hypercalcemia, hyperlipidemia, hyperglycemia & hyperuricemia
 are the side effects of _____. hydrochlorothiazide (HydroDIURIL)
Thiazide diuretics are considered to be ____ “potassium-wasting”
When Thiazide diuretics are used ______is the electrolyte imbalance most often seen Hypokalemia
Orthostatic hypotension Hypokalemia (exception: K+ sparing diuretics such as spironolactone) Hyponatremia are common side effects for___? Of diuretic drug therapy:
Monitor renal function & urine output Daily weight Postural blood pressure checks; are nursing consideration for diuretic drug therapy
Client change positions slowly & rise slowly Monitor HR & rhythm Assess skin & mucous membranes Monitor serum Na and K+ levels Increased excretion of all medications Administer in the morning or early afternoon; are nursing consideration for diuretic drug therapy
Adrenergic Drugs Exert their action at ___ sites different
Clonidine, guanfacine, methyldopa stimulate a-2 adrenergic receptors in the ___ brain
Clonidine, guanfacine, methyldopa are ____ acting Central action ( in the brain)
Doxazosin, prazosin, terazosin block ___ receptors, dilating arteries & veins to reduce PVR & thus reduce ___. a-1 adrenergic; BP
Doxazosin, prazosin, terazosin are ____ action Peripheral action (at the heart & blood vessels)
Propranolol & atenolo block ___ receptors and reduce ____ secretion block b-1 receptors & reduce renin secretion
(labetalol, carvedilol (Coreg)) are ____which reduce HR and ____vessels Dual action a1 & b receptor blockers; dilate
Created by: jwhite223
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