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Pharmacology

CARDIOVASCULAR & RENAL SYSTEMS Antilipemic agents

QuestionAnswer
Antilipemic agents treat conditions associated with excess _____ in the ____ stream. cholesterol in the blood stream
What are the four types of lipids? 1.Chylomicrons 2. Very low density lipoproteins [VLDL] 3. Low density lipoprotein [LDL] 4. High density lipoprotein [HD
What are the two primary forms of lipids in the blood? triglycerides & cholesterol
_____ are an energy source, & are stored in _____tissue Triglycerides; adipose
Cholesterol is primarily used to make ______cell membranes, & _______. steroid hormones, bile acid
Where does lipid metabolism occur? Liver
Antilipemic drugs are used to _____ high levels of ____within blood lower; lipids
How do you treat high cholesterol? Drugs Life Style Changes
What are the major antilipemic drugs? 1. HMG-CoA reductase inhibitors 2.Bile acid sequestrates 3. Niacin 4. Fibric acid derivatives 5. Cholesterol absorption inhibitor (Zetia)
HMG-CoA Reductase Inhibitors are also known as ____ Statins
HMG-CoA Reductase Inhibitors _____HMG-CoA enzyme to _____cholesterol concentration in the blood stream, which (↓cholesterol production) Inhibit ; decrease
Atorvastatin (Lipitor) is a HMG-CoA Reductase Inhibitors
What are the side effects of Lipitor and HMG-CoA reductase inhibitors? GI disturbance, ↑ liver enzyme levels
Bile Acid Sequestrants are released in ___ intestine
Bile Acid Sequestrants allows the ___ to releases cholesterol to bind to bile acids liver
BIle Acid Sequestrant binding to the liver leads to____absorption in intestine (↓cholesterol absorption) decreasing
Cholestyramine (Questran is a _____. Bile Acid Sequestrant
Fibric Acid Derivatives are a class of medication that ______ triglyceride levels. re a class of medication that lowers blood triglyceride levels.
emfibrozil & clofibrate synthesis of ____ VLDL
What is the most common side effects for Fibric Acid Derivatives? GI irritation
is effective intreating in most _____ hyperlipidemias
There are a few patients that can tolerate ________ . Nicotinic acid /niacin/vitamin B3
If Patient experiences flushing, itching, peptic ulcer, diabetic intolerance you should ____ use. Discontinue use
What are side effects for antilipemics that you should teach your patient to notice? 1.Muscle pain, 2.other unexplained pain 3. GI upset, constipation 4. Yellow discoloration of skin 5. Decreased sex drive
Regarding antilipmic agents you must monitor ____ and ___ functions. Monitor liver and renal function
You should monitor _____ function when taking antilipemic agents. Monitor cholesterol level
You must give antilipemic meds during _____ meal time with ___ of water. evening; 120 to 180 ml of water
You should not ____ antilipemic pills. crush
When on antilipemic pills you should drink__ ml of water a day. Drink at least 2000 ml water each day
Created by: jwhite223