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Anemia

QuestionAnswer
macrocytic anemia folate, B12 deficiency, pernicious anemia , megaloblastic
pernicious anemia lack of intrinsic factor
normocytic, normochromic acute blood loss, aplastic anemia - marrow fails to make three types of blood cells - anemia, neutropenia (decrease WBCs), and thrombocytopenia (decrease platelets); drugs that cause this are felbamate, chloramphenicol, phenytoin
hypochromic, microcytic anemia IDA, sickle cell, thalassemia
anemia of renal failure lack of EPO
IDA labs lookl like... decrease in ferritin, decrease in iron, decrease in Hgb, increase TIBC
IDA symptoms koilonmychias, angular stomatitis, glossitis, pica
megaloblastic anemia looks like... decrease in Hct, Hgb, decrease in RBC, increase in MCH
What has neuropsychiatric symptoms? B12 deficiency, not folate
iron supplement PO per day 200 elemental per day
ferrous sulfate 65 mg; feosol, fer-in-sol
ferrous gluconate 35 mg; fergon
ferrous fumarate 99 mg; femiron, feostat
iron dextran infed
iron sucrose venofer
sodium ferric gluconate ferlecitt
iron counseling points take on empty stomach, can take with OJ, can use OTC docusate if have constipation
iron ADRs dark colored stools, constipation, diarrhea, N/V
recommended daily intake of Vitamin B12 2 mcg/day
vegan should get this much B12 per day 1000 mcg/day
IM cyanocobalamine (B12) 1000 mcg IM QD x 1 week, then 100-1000 mcg QW x 4 weeks; then 100-1000 mcg QM
B12 ADRs hyperuricemia, hypokalemia, sodium retention, cardiac problems, itching, diarrhea, anaphylaxis
EPO ADRs immunogencity : pure red cell aplasia, increase in BP
Darbo ADRs HTN, hypotension, edema, arrhythmia, N/V, diarrhea, constipation, fatigue, fever, HA, myalgia, arthralgia, limb pain, infection, dyspnea, cough
Created by: cytoskeletor
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