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Anti-infectives
Misc Antibiotics, Antifungals, antitubuculosis agents
| Question | Answer |
|---|---|
| clindamycin spectrum | active against most aerobic gram +, and anaerobic gram - |
| clindamycin ADRs | GI effects, c. diff, thrombophlebitis, platelet functions |
| imipenam-cilastin | Primaxin |
| imipenem-cilastin spectrum | very broad, but doesnt cover MRSA or MRSE |
| imipenem-cilastin ADRs | GI, platelets, seizures |
| meropenem | merrem; similar to imipenem except decrease in CNS toxicity and no hydrolysis of dehydropeptidases |
| Ampho B spectrum | aspergillosis, coccidio, crypto, histoplasma, mucor; candida - albicans, dublinesis, glabrata, krusei, parapsilosis, tropicalis (Kim Ate The Good Pineapples in Dublin) |
| Ampho B ADRs | infusion reactions, renal and electrolyte effects, hematologic, hepatic |
| Ampho B lipid formulations | Abelcet, Amphotec, AmBisome |
| Caspofungin spectrum | aspergilosis |
| Caspofungin ADR | increase AST, ALT, sensitivity reactions, infusion reactions |
| Fluconazole spectrum | Krusei, Glabrata, Albicans, Tropicalis, Parapsilosis, Lusitaniae (Kevin Luckily Ate The Good Pineapples) |
| Fluconazole ADRs | GI effects, hepatic effects, hemolytic effects, nervous system effects |
| Flucytosine spectrum | most candida strains and cryptococcus |
| Flucytosine ADRs | GI, hepatic, renal effects, nervous system, sensitvity reations |
| Griseofulvin spectrum | trichophyton, microsporum, epidermophyton |
| Griseofulvin ADRs | nervous system, GI, renal,proteinuria, sensitivity |
| Itraconazole spectrum | aspergilosis, blastomycosis, histoplasmosis, orapharyngeal and esophageal candidiasis, mycho, coccidio, cryptococcus |
| itraconazole ADRs | GI, dermatologic, nervous system, QT prolongation, increase in AST/ALT, electrolyte |
| ketoconazole spectrum | blastomycosis, candidiasis, coccidio, histoplasmosis, dermatophytosis |
| ketoconazole ADR | GI, hepatic, endocrine, gynecomastia, decrease in cortisol, dermatologic, nervous system effects |
| Nystatin spectrum | cutaneous and mucouscutaneous candidiasis |
| Nystatin ADR | nausea and diarrhea |
| Terbinafine spectrum | trichophyton, microsporum, epidermophyton, aspergilosis, blastomycosis, yeasts |
| terbinafine ADR | hepatic effects, derm --> SJS |
| voriconazole spectrum | aspergilosis |
| voriconazole ADR | hepatic, derm --> SJS |
| aminosalicylic acid ADR | GI, vitamin and mineral absorption, hypersensitivity |
| Capreomycin ADR | nephrotoxicity, otoxocity, hepatic, hypersensitivity |
| cyclosporine ADR | HA, vertigo, confusion, psychosis, seizures |
| ethambutol ADR | ocular effects |
| Isoniazid ADR | CNS - peripheral neuritis, seizures, encephalopathy, psychosis; increase AST or ALT, hematologic |
| Pyrazinamide ADR | hepatic effects, gout |
| rifampin ADR | GI, c. diff, CNS, hepatic effects, hematologic, renal effects |
Created by:
cytoskeletor
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