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Osteoarthritis
| Question | Answer |
|---|---|
| Clinical symptoms | pain, joint stiffness in morning too but shorter in duration and resolves with activity; crepitus in knee, Herbendens, Bouchards, osteophytes in DIP and PIP |
| Patho | collagen fibers destroyed, cartilage thins |
| Diagnosis | Hip pain + osteophytes, joint narrowing, ESR<20; knee pain + >50 years, morning stiffness <30 minutes, crepitus |
| Hip treatment | nonopioid analgesiscs (APAP), NSAIDs, opioid analgesics (codeine, propoxyphene, oxycodone) |
| Knee treatment | intra-articular steroids (Hyaluronic acid), APAP, capsaicin, methylsalicylate cream, NSAIDs, opioids (propoxyphene, codeine, oxycodone) |
| Preventative treatmenet | glucosamine, choindrotin; not recognized by arthritis foundation |