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IBS

Inflammatory Bowel Syndrome

QuestionAnswer
Types of IBS diarrhea predominant; constipation predominant; diarrhea and constipation
clinical presentation of IBS ab pain exacerbated by meals, upper GI symptoms with constipation (heart burn, dyspepsia, early satiety and nausea), ab distention, bloating, pelvic pain, dysmenorrhea, dysparemia, urinary frequency, nocturia, imcomplete bladder evacuation, decrease sexua
Alarm symtpmos onset <50 years; unexplained weight loss, GI bleeding, progressive or unrelenting pain, nocturnal or large volume diarrhea, family history of colon cancer, IBD, iliac sprue
Dicyclomine Bentyl; antispasmodic; anticholinergic; used in mild diarrhea
Hyoscyamine anticholinergic
Amitriptyline Elavil; anticholinergic; used in diarrhea
Paroxetine Paxil; SSRI; used for psychiatric comorbidities
Tegaserod Zelnorm; 5HT3 antagonist; used in constipation
Lactulose osmotic laxative
polycarbophil fibercon; bulking agent
PEG osmotic laxative
alosetron lotronex; 5HT3 antagonist
alosetron ADRs constipation, ab pain, nausea, intestinal obstruction, ischemic colitis, toxic megacolon, death; have to sign manufacturer agreement; use no more than 4 weeks
loperamide imodium; antidiarrhea
diphenoxylate/atropine lomotil; antidiarrhea
Created by: cytoskeletor
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