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GI diseases
| Question | Answer |
|---|---|
| Omeprazole | Prilosec |
| Esomeprazole | Nexium |
| Lansoprazole | Prevacid |
| Rabeprazole | Aciphex |
| Pantoprazole | Protonix |
| Cimetidine | Tagamet |
| Ranitidine | Zantac |
| Nizantidine | Axid |
| Famotidine | Pepcid |
| Ranitidine Bismuth citrate | Tritec |
| Sucralfate | Carafate |
| Bismuth ADRs | black tarry stools |
| Sucralfate ADR | constipation |
| Furazolidone ADR | N/V, HA, tachy, HTN, MAOI, disulfiram reaction |
| Magnesium Hydroxide | Milk of Magnesia |
| Aluminum Hydroxide | Amphojel, AlternaGel |
| Aluminum carbonate | Basaljet |
| Magnesium Hydroxide+ Aluminum Hydroxide | Maalox |
| Magaldrate | Riopan |
| Carlcium carbonate | Tums, Titralac |
| Alginic Acid + Aluminum hydroxide +Magnesium hydroxide | Gaviscon |
| Drugs that decrease LES pressure | CCBs, B-blockers, nitrates, barbituates, anticholinergics, theophylline |
| drugs that increase LES pressure | tetracycline, NSAIDs, ASA, bisphosphonates, iron, quinidine, KCL |
| two types of inflammatory bowel disease | ulcerative colitis and crohns disease |
| mild presentation of IBD | <4 stools/day with or without blood; without systemic disturbance, with normal ESR |
| moderate presentation of IBD | >4 stools/day with minimal signs of toxicity |
| severe presentation of IBD | >6 stools/day with blood, systemic disturbance, and ESR>30 |
| fulminant of IBD | >10 bowels/day, continuous bleeding, toxicity, ab tenderness or distended, blood transfusion requirement, colonic dilation on abdominal plain films |
| treatment for distal UC that involves only the rectum | 1) topical aminosalicylates for two-three weeks; 2) rectal steroids; 3) oral amino and/or steroids |
| treatment for mild to moderate distal colitis | PO aminos; topical mesalamine or topical steroids; if refractory, use oral steroids; (combining PO aminos and topical aminos better than just using one) |
| maintenance of remission of distal ulcerative colitis | mesalamine enemas every third night; oral aminos |
| moderate to severe distal colitis treatment | BID enemas, PO aminos+topical aminos |
| severe distal colitis treatment | PO corticosteroids if failed aminos; taper CS once get remission and continue PO/topical aminos as maintenance therapy |
| mild to moderate extensive ulcerative colitis treatment | 1) PO aminos; 2) high dose PO CS (no role in maintenance therapy); 3) azathioprine, mercaptopurine |
| moderate to severe extensive ulcerative colitis | infliximab |
| severe/fulminant extensive ulcerative colitis treatment | hospitalization and bowel rest; IV steroids; surgery; IV Cyclosporine; Azathioprine for maintenance therapy |
| mild to moderate Crohn's disease treatment | PO aminos; flagyl or cipro; both more effective for colonic than ileal CD |
| mild to moderate gastroduodenal CD treatment | H2Bs or PPIs |
| moderate to severe CD treatment | 1) PO prednisone/PO Budesonide; 2) Azathioprine; 3) 6 Mercaptopurine; 4) MTX or Infliximab for maintenance |
| Severe or fulminant CD treatment | hospitalization for IV steroids, hydration; metro or cipro for fistulas; surgery; Azathioprine, Mercapto, Infliximab, PPIs + Octreotide for fistulas; cyclosporine, tacrolimus; Mercapto is best for preventing relapse of CD after surgical intervention |
Created by:
cytoskeletor
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