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HIV medication
drugs for class to know
| GENERIC NAME | ABREVEATION | special info to know |
|---|---|---|
| zidovudine | AZT, ZDV | crosses blood brain barrier |
| didanosine | ddI | take with antacids crosses BBB use with caution in dementia cases cause neuropathy |
| zalcitabine | ddC | use with caution in dementia cases neuropathy |
| stavudine | d4T | crosses BBB use with caution in dementia cases causes neuropathy |
| lamivudine | 3TC | (blank) |
| abacavir | ABC | (blank) |
| tenofovir DF | TDF | eat with fatty meal |
| indinavir | IDV | NO Antacids |
| ritonavir | RTV | Auto induction inhibits 3A4 HIV-1 and HIV-2 increases cholesterol adn triglycerides |
| saquinavir | SQV | take with fatty food inhibits 3A4 the least of the PI's |
| nelfinavir | NFV | should eat with fatty meal autoinduction has active metabolite |
| lopinavir/ritonavir | LPV/r | eat with fatty meal |
| nevirapine | NVP | (blank) |
| delavirdine | DLV | (blank) |
| efavirenz | EFV | eat with fatty meal use with caution in dementia cases impaired concentration adn depersonalizaiton |
| atazanavir | ATV | fatty food increases bioavailability while increasing the pH redues bioavailability. so don't take with PPI, H2 antagonist or anacids |
| darunavir | (blank) | always used with ritonavir. food increase bioavailablity, may increase blood sugar, bleeding time, and change body fat distribution, AVOID if sulfa allergy, diabetic, hemophillia, liver problems |
| (abacavir + zidovudine + lamivudine), | (blank) | use with caution in dementia cases |