Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Women's Health
Menopause, Oral Contraceptives, Osteoperosis
| Question | Answer |
|---|---|
| Oral hormone replacement therapy | Premarin, Estradiol, Estrace, Gynodiol, Estropipate, Ortho-Est, Ogen, Estratab, Menest |
| Estradiol Transdermal Formulations | Estraderm, Alora, Climara, Esclim, Vivelle, Vivelle--Dot |
| Injectable estrogens | delestrogen |
| Vaginal estrogen formulations | estrace vaginal cream, ogen vaginal cream, premarin vaginal cream, vagifem vaginal tablet |
| Combination estrogen-progestin products | activella, femhrt, prempro, premphase, climara pro, combipatch |
| combination estrogen-androgen products | estratest HS, synthest HS, estratest, syntest DS |
| estrogen side effects | breast tenderness, heavy bleeding, headache, nausea |
| progestin side effects | depression, HA, irritability |
| estrogen + progestin | combined oral contraceptives (COC) |
| protestin-only (minipill) | appropriate for breast feeding women; efficacy is less than COC; free of CV risks |
| estrogens examples | ethinyl estradiol, mestranol |
| progestin examples | desogestrel, norgestrel, levonorgestrel, ethynodiol diacetate, norethindrone, norethynodrel |
| estrogen MOA | suppresses FSH, does not block ovulation |
| progestin MOA | blocks ovulation; creates impermeable cervical mucus; contributes to atrophy of endometrium |
| drugs that decrease OC | ampicillin, griseofulvin, sulfonamides, tetracycline, anticonvulsants, NNRTI's, PI's, pioglitazone, phenytoin, rifampin, theophylline |
| drugs that increase OC | atorvastatin, vit C, 3A4 inhibitors |
| OC decreases these drugs | anticoags, BZDs, hypoglycemics, methyldopa, phenytoin |
| OC increases these drugs | TCAs, BZDs, Beta blockers, theophylline |
| OC will increase the toxicity of this drug | cortisone |
| progestin only OC | Ortho micronor, Errin, Nor-QD, Nora-BE, Camila, Ovrette |
| monophasic low-dose estrogen OC | Alesse, Aviane, Lessina, Levlite, Loestrin, Microgestin FE, Yasmin, Levlen, Levora, Nordette, Portia, Seasonale, Cryselle, Lo/Ovral, Low-Ogestrel, Apri, Desogen, Ortho-cept, Ovcon-35, Brevicon, Necon, Nortrel, Ortho-Novum, Norinyl, Kariva, Mircette |
| Monophasic-high dose estrogen OC | ovral, ogestrel, demulen, Zovia, ovcon-50, necon, norinul, ortho-novum |
| Biphasic oral contraceptives | ortho-novum, necon |
| triphasic oral contraceptives | enpresse, tri-levlen, triphasil, trivora, tri-norinyl, necon, ortho-novum, cyclessa, otho-tricyclen lo, ortho-tricyclen, estrostep |
| transdermal OC | ortho evra |
| vaginal ring OC | nuva ring |
| contraceptive injection | depo-provera, lunelle |
| intrauterine contraceptive systems | progestasert, mirena |
| CI for COC use | breast cancer, DVT, PE, CVA or CAD, IHD, diabetes with nephropathy, neuropathy, retinopathy, headaches, hypertension (160/100), lactation (<6 weeks postpartum), liver disease, pregnancy, surgery with prolonged immobilization, structural heart disease |
| estrogen excess side effects | breast tenderness, fullness, cervical mucorrhea, edema, hypertension, melasma, migraine, nausea, bloating |
| progestin excess side effect | acne or oily scalp, breast regression, deprssion, hypomenorrhea, increased appetite, monilial vaginitis, tiredness, fatigue, weight gain |
| estrogen deficiency side effects | breakthrough bleeding, hypomenorrhea, spotting |
| progestin deficiency | amenorrhea, breakthrough bleeding, hypermenorrhea |
| drugs that increase the risk of osteoperosis | anticonvulsants, cytotoxic drugs, glucocorticoids, immunosuppressants, lithium, long term heparin use, progesterone, supraphysiological thyroxine doses, tamoxifen |
| initiation of therapy begins with these T scores | T score < -2.5 with no risk factors; T score < -1.5 with risk factors |
| Calcium Carb/Vit D | 1000-1500 mg/day for calcium; 400-800 U/day for vitamin D; caltrate 600 + D, calcilyte + Vitamin D, Oscal + Vit D |
| calcium carbonate | caltrate 600, tums, titralac, viactiv chews, mylanta lozenges |
| calcium citrate | citracal |
| Treatment for osteopersosis | Calcium + Vit D, Bisphosphonates, estrogen replacement therapy, selective estrogen receptor modulator, calcitonin, teriparatide |
| Bisphosphonates | Alendronate (Fosamax); Ibandronate (Boniva); Risedronate (Actonel); for treatment and prevention of osteoperosis |
| Alendronate dose | Prevention: 5 mg QD or 35 mg QW; Treatment: 10 mg QD or 70 mg QW |
| Ibandronate dose | 150 mg QM for prevention and treatment |
| Risedronate dose | Prevention: 5 mg QD; Treatment: 5 mg QD or 30 mg QW |
| Patient counseling on Bisphosphonates | take with full glass of water 30 minutes prior to first meal of day; stand upright for 30 minutes |
| DDIs of Bisphosphonates | calcium supplements (separate by 1 hour); Ranitidine, ASA increases GI side effects |
| Raloxifene ADRs | hot flashes, chest pain, syncope, nausea, diarrhea, vomiting, arthralgia, myalgia, insomnia, neuralgia, rash, sweating |
| Raloxifene DDI's | cholestyramine, ampicillin, warfarin |
Created by:
cytoskeletor
Popular Pharmacology sets