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Hypothyroid Drugs
| Question | Answer |
|---|---|
| ADRs of thyroid drugs | CV, CNS, GI, weight loss, fatigue, menstrual irregularity, excessive sweating, heat intolerance, fever, muscle weakness, hair loss, decreased bone mineral density, hypersensitivity |
| Drug interactions | amiodarone, antacids, antidiabetics, resins, antiepileptics, estrogens, lithium (causes hypothyroidism), warfarin, digoxin, sucralfate, soybean, sympathomimetic, theophylline |
| T4 drugs | Synthroid, Levothroid, Levoxyl, Unithroid, Thyro-tabs |
| Dessicated thyroid | armour thyroid, nature-thyroid, westhroid |
| T3 (liothyronine drugs) | Cytomel, Triostat |
| Liotrix (T4 and T3 in 4:1 ratio) | Thyrolar |
| miscellaneous info about dessicated thryoid | dessicated thyroid discouraged because less predictable potency and stability compared to levothyroxine |
| misc info about T3 (liothyronine) | shorter half life than levothyroxine and high incidence of cardiac effects |
| hypothyroidism mainly caused by? | Hashimoto's; pituitary failure causes secondary hypothyroidism; hypothalamic failure causes tertiary hypothyroidism |