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Skeletal Muscle Rela

Pharmacology for Skeletal Muscle Relaxants

QuestionAnswer
INdication for cyclobenzaprine musculoskeletal pain, muscle spasm
Indication for tizandidine spasticity
Indication for baclofen spasticity resulting from MS and spinal cord trauma
MOA OF CNS Depressants unknown, effects achieved on localized spasms through production of sedation
This class of drugs is ineffective in treating muscle spasticity from CNS disease CNS depressants
Metaxalone (Skelaxin) Drug Class CNS depressant
Methocarbamol (Robaxin) Drug Class CNS depressant
Carisprodol (Soma) Drug Class CNS Depressant
MOA of TCA Relative acts on CNS to reduce tonic somatic motor activity
Cyclobenzaprine (Flexeril) Drug Class TCA Relative
A2 Adrenergic Receptor Agonist Tizanidine
Tizanidine used for ___ and ___ spasms peripheral;central
Drug that is a GABA Receptor Stimulants for Skeletal Relaxants Baclofen
Baclofen is effectly only for muslce spasms by peripheral or central diseases central
MOA for GABA Receptor Stimulant inhibits synaptic reflexes at the spinal leve and is a structural analog of GABA (the inhibitory neurotransmitter)
Use nonpharmacologic therapy for skeletal relaxants for only ____ hours 1st 24-48 hours
1st line analgesic for muscle relaxants NSAIDS, acetaminophen
2nd line analgesic for muscle relaxants muscle rlaxant tramadol, opiosds if severe or debilitating
1st line muscle relaxant cyclobenzaprine, CNS sedatives
Patient Education for muscle relaxants sedation, no etoh (r/t cns depressants furthered), use for short periods, no children less than 12yo
Created by: sbsmithrn
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