Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Pharm Ch. 44
Antiinflammatory and Antigout
| Question | Answer |
|---|---|
| What is inflammation? | A localized protective response stimulation by injury to tissues that serve to destroy, dilute, or wall off both the injurious agent and the injured tissue |
| What is gout? | Hyperuricemia, the arthritis caused by tissue buildup of uric acid crystals |
| What properties do NSAIDs have? | Analgesic, antiinflammaroty, antirheumatic, and antipyretic(fever) |
| Name the 5 cardinal signs of inflammatin | 1.erthema(redness) 2.edema(swelling) 3.heat(fever)4.pain 5.loss of function |
| Prostaglandins (Prostaglandin Pathway) | vasodilation, capillary permeability, pain, fever |
| COX (cyclo-oxygenase) | enzyme that converts arachidonic acid into prostaglandins |
| Name the 5 NSAID groups | 1.Salicylates 2.Acetic Acid Derivatives 3.COX 2-inhiitors 4.Enolic Acid Derivatives 5.Propionic Acid Derivatives |
| Salicylates Drugs | 1.Aspirin 2.Diflunisal 3.Salsalate 4.Choline Salicylate |
| Salicylates Actions | Antiinflammatory, antiplatelet, antipyretic |
| NSAIDs Indications | Acute Gout, Acute gout arthritis, Ankylosing Spondyilitis, Bursitis, Fever, Rheumatoid Arthritis, Mild to Moderate pain, |
| NSAID Adverse Effects and Drugs that help | CV-noncardiogenic pulmonay edema, GI-indigestion, GI bleeding-dyspepsia Mucosal lesions misoprostol(Cytotec)- reduce effects, induce labor |
| NSAID Conteraindications | Rhinitis, Vit K deficiency, Peptic ulcer, Aspirin Allergy |
| Salicylism | Salicylate toxicity Sx - tinnitus, ototoxicity, nausea, vomiting Mild-Stop Treatment, Severe - Dialysis |
| Salicylate Conterindication | Children with flulike Sx- associated with Reye's Syndrome, encephalopathy, liver shutdown |
| Name some Acetic Acids | Indocin, Toradol, Voltaren, Clinoril, tolectin, lodine, ponstel |
| Name COX-2 inhibitor | Celebrex Used for arthritis, dysmenorrhea(painful period) |
| Name Enolic Acid Derivatives | Piroxicam(Feldene), Meloxican(Mobic), Namumetone(Relafen) |
| Name Propionic Acids | Nalfon, Ansaid, Motrin, Advil, Naprosyn,Aleve, Daypro |
| Antigout Drugs | Allpurinol-prevent uric acid production Colchicine-reduce inflammation Probenecid-incr excretion of uric acid in urine |
| Allopurinol Skin Adverse Effects | Exfoliative dermatitis, Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis |
| Nursing Implication | Assess for Contraindications, Preform Laboratory Test, Medication history, Take with milk or antacid, therapeutic affects 3-4 weeks, Monitor therapeutic effects, |
Created by:
mary_ray
Popular Pharmacology sets