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RT 230 Ch 1,2

Pathology for RTs

QuestionAnswer
Acute Having a quick onset and lasting a short period of time with a relatively severe course
Asymptomatic showing or causing no identifiable symptoms
Acute Having a quick onset and lasting a short period of time with a relatively severe course
Asymptomatic showing or causing no identifiable symptoms
Atrophy a reduction in size or wasting of cells, tissues, or organs as a result of poor nutrition or nonuse
Carcinoma a malignant growth composed of epithelial cells that tends to invade surrounding tissues and give rise to metastases
Autoimmune disorders disease in which antibodies form against and injure the pt's own tissue, in contrast to the normal process in which antibodies form in response to foreign antigens
Chronic presenting slowly and persisting over a long period of time
Congenital existing at, and usually before, birth and resulting from genetic or environmental factors
Debridement removal of dead cells and materials
Benign neoplasm refers to a localized and generally noninvasive lesion
Degenerative refers to deterioration of the body usually associated with the aging process
Carcinoma a malignant growth composed of epithelial cells that tends to invade surrounding tissues and give rise to metastases
Diagnosis the name of a disease an individual is believed to have
Chronic presenting slowly and persisting over a long period of time
Dysplasia abnormal tissue development
Epidemiology the investigation of disease in large groups
Congenital existing at, and usually before, birth and resulting from genetic or environmental factors
Debridement removal of dead cells and materials
Degenerative refers to deterioration of the body usually associated with the aging process
Destructive disease process decreases the normal tissue density
Diagnosis the name of a disease an individual is believed to have
Disease any abnormal disturbance of the normal function or structure of a body part, organ, or system
Dysplasia abnormal tissue development
Hypertrophy is a generalized increase in cell size
Epidemiology the investigation of disease in large groups
Iatrogenic pertains to any adverse condition that occurs in a patient as a result of medical treatment
Etiology the study of the cause and origin of disease
Idiopathic having no identifiable causative factor
Hematogenous spread spread thru the blood
Incidence a statistical measure that refers to the number of new cases of a disease found in a given time period
Hereditary genetically transferred from either parent to child and derived from ancestors
Infection an inflammatory process caused by exposure to some disease causing organism
Hyperplasia is an increase in the number of cells in tissue as a result of excessive proliferation
Invasion when cancerous cells spread into surrounding tissue by virtue of the close proximity of the areas
Homeostasis the body's normal, internal resting state of eqilibrium
Hypertrophy is a generalized increase in cell size
Iatrogenic pertains to any adverse condition that occurs in a patient as a result of medical treatment
Idiopathic having no identifiable causative factor
Incidence a statistical measure that refers to the number of new cases of a disease found in a given time period
Infection an inflammatory process caused by exposure to some disease causing organism
Invasion when cancerous cells spread into surrounding tissue by virtue of the close proximity of the areas
Metabolism is the sum of all physical and chemical processes in the body
Lesion general term used to describe the various types of cellular change that can occur in response to a disease
Leukemia a malignant disease of the leukocytes and their precursor cells in the blood and bone marrow
Lymphoma neoplastic growth in the lymphatic system
Lymphatic spread spread thru the lymphatic system
Malignant neoplasm refers to a lesion that grows, spreads, and invades other tissues
Manifestations observable changes resulting from cellular changes in the disease process
Metabolism is the sum of all physical and chemical processes in the body
Metaplasia is a conversion of one cell type into another cell type that is not normal for that tissue
Metastatic spread the spread of cancer cells
Morbidity rate the incidence in the population of illness sufficient to interfere with an individual's normal daily routine
Mortality rate the number of deaths from a particular disease averaged over a population
Neoplastic pertaining to new, abnormal tissue growth
Nosocomial refers to diseases acquired in or from a health care environment
Pathogenesis development of disease
Prevalence a statistical measure that refers to the number of cases of a disease found in a given population
Prognosis the prediction of course and outcome for a given disease
Sarcoma a type of tumor, often highly malignant, composed of a substance like embryonic connective tissue
Sclerotic disease process increase in normal tissue density
Seeding the traveling of cancerous cells to a distant site or distant organ
Sign an objective manifestations of disease perceptible to the managing physician, as opposed to subjective symptoms perceived by the patient
Symptom any subjective evidence of a disease as perceived by a patient
Syndrome a group of signs and symptoms that occur together and characterize a specific abnormal disturbance
Traumatic pertaining to the effects of a wound or injury, whether physical or psychic
Virulence the ease with which an organism overcomes body defenses
Albers-Schonberg disease a form of osteosclerotic osteopetrosis; a benign skeletal anomaly that involves increased bone density in conjunction with fairly normal bone contour
Ankylosing spondylitis a form of rheumatoid arthritis of unknown cause that effects the spine in a progressive fashion, eventually fusing the spine into a rigid block of bone
Arthritis inflammation in which lesions are confined to the joints
Bursitis inflammation of the bursae of the tendons, with the subdeltoid bursa as the most common site
Cancellous bone refers to the spongy, lattice-like structure of bone filled by bone marrow
Chondrosarcoma a malignant bone tumor composed of atypical cartilage
Clubfoot deformity of the foot involving the talus
Compact bone refers to the dense, outer portion of bone
Developmental dysplasia of the hip a malformation of the acetabulum , acetabulum does not completely form, the head of the femur is displaced superiorly and posteriorly
Diaphysis shaft of a long bone
Diploe the spongy bone tissue found between the two tables of the cranial bones
E. coli (escherichia) species of ameba normally found in the upper intestinal tract
Epiphysis an ossification or growth center in the bones of children
Ewing's sarcoma a primary malignant bone tumor arising in medullary tissue, occurring more often in cylindric bones, occurs mainly in 5 to 15 year olds
Exostosis a benign bone growth, projecting outward from the bony cortex
Ganglion cystic swelling that develops in connection with a tendon sheath, usually on the back of the wrist
Giant cell tumor (GCT) a neoplastic growth of the skeletal system consisting of numerous multinucleated osterclastic giant cells, also called osteoclastoma
Gouty arthritis an inherited, metabolic disorder with excess amounts of uric acid produced and deposited in the joint and adjacent bone, most commonly in the metataursophalangeal joint of the great toe
Involucrum a shell or sheath of new supporting bone laid down by periosteum around a sequestrum of necrosed bone
Juvenile rheumatoid arthritis Still's disease, affects children under 16 and is similar to adult RA.
Medullary canal inner spongy or cancellous portion of a long bone where bone marrow is produced
Metaphysis the growing portion of bone
Osteoartritis noninflammatory degeneration joint disease occurring mainly in older persons, producing gradual deterioration of the joint cartilage
Osteoblasts the bone-forming cells responsible for bone growth, ossification, and regeneration
Osteochondroma a benign tumor of adult bone capped by cartilage
Osteoclastoma a tumor that is usually benign and characterized by osteolytic areas
Osteoclasts cells that are associated with absorption and removal of bone
Osteogenesis imperfecta a congenital disease in which the bones are abnormally brittle and subject to fracture
Osteoma benign bone tumor most commonly located in the skull, with dense bone tissue that usually objects into the orbits or paranasal sinuses
Osteomyelitis infection of bone, most often caused by staphylococcus, which may localize or spread to the bone to involve the marrow and other bone tissues
Osteopetrosis a hereditary disease characterized by abnormally dense bone, likely as a result of faulty bone resorption
Osteosarcoma a primary malignancy of bone usually arising in the metaphysis, most commonly around the knee, arises from osteoblasts
Polydactyly the presence of more than five digits
Pott's disease a fracture of the lower part of the fibula involving both malleoli with dislocation of the ankle joint
Rheumatoid arthritis a chronic, systemic disease primarily of joints, characterized by an overgrowth of synovial tissues, and articular structures and progressive destruction of cartilage, bone, and supporting structures
Scoliosis abnormal lateral curvature of the spine
Sequestrum a piece of dead, devascularized bone that separates from living bone during the process of necrosis
Spina bifida a developmental anomaly characterized by incomplete closure of the vertebral canal, thru which the choriomeninges may or may not protrude
Spondylolisthesis L5-S1. forward displacement of one vertebra over another, usually caused by a developmental defect in the pars interarticularis
Spondylolysis a condition marked by a cleft or breaking down of the body of a vertebra between the superior and inferior articular processes
Syndactyly a webbing or fusion of digits
Tendonitis inflammation of a tendon
Tenosynovitis inflammation of a tendon and its sheath
Trabeculae weblike bony structure
Trabecular pattern trabeculae is visible on a properly exposed radiograph of the skeletal system
Tuberculosis any of the infectious disease of man and animal caused by mycobaterium tuberculosis, generally affecting the lungs in the human body
Whiplash hyperextention-flexion injury of the spine
Craniosynostosis congenital anomaly, premature or early closure of any cranial sutures
Primary sites for metastatic bone cancer? Breast, lung, prostate, kidney, thyroid, and the bowel
Is bone mainly a primary or secondary tumor site? Secondary
What tumors are benign? Osteochondroma and Osteoma
What tumor can be benign or malignant? Giant cell tumor (osteoclastoma)
What tumors are malignant? Osteosarcome, Ewing's tumor, Chondrosarcoma
What imaging that shows whether pathology is new or old, metabolic process, look at whole body at once? Nuclear Medicine
What imaging is imaging of choice for soft tissue tumors, superior contrast resolution, superior bone? MRI
What imaging is fast and non-invasive and has good bone detail? CT
What imaging detects bone mass and bone density? DEXA (bone mineral densitometry
Created by: Chrslarsen
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