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antiepileptic agents
Pharm
Question | Answer |
---|---|
the unpleasant state of mind in which unreal or imagined dangers are anticipated | Anxiety |
A state charcterized by an expansive, emotional state (including symptoms of extreme exitement and elation) and hyperactivity | Mania |
A group of psychotropic agents prescribed to alleviate anxiety | Benzodiazepines |
Emotional disorders charcterized by changes in mood | Affective Disorders |
Classified as a monoamine oxidase inhibitor (MAOI) | Phenelzine |
Patients on MAOIs need to be taught to avoid food that contain this substance | Tyramine |
Antidepressants agents that block reuptake of amine neurotransmitters | Tricyclics |
An abnormal emotional state charcterized by exaggerated fellings of sadness, melancholy, and worthlessness out of proportion to reality | Depression |
The most frequently prescribed Benzodiazepine | Diazepam |
The most widely used Tricyclic antidepressant | Amitriptyline |
An atypical antipsychotic agent used to treat schizophrenia | Resperidone |
A second-generation antidepressant | Sertraline |
the drug of choice for mania | Lithium |
A term used to describe a major emotional disorder that impairs the metal function of the affected individual to the extent that the individual cannot participate in every day life | Psychosis |
Patients taking newer antipsychotic agents such as quetiapine (Seroquel) should be cautioned about which problem? | Postural hypotension |
When starting an antidepressent therapy, How long will it take to feel better? | 4 to 6 weeks |
Extrapyamidal effects include | spasmodic movement of limbs and the inability to sit still, parkinsonian-like symptoms (mask-like facial expressions), involuntary motor restlessness |
Patient on MAOI therapy must avoid Tyramine containing foods in order to prevent which medical condition? | Severe hypertensive crisis |
Abnormal levels of endogenous chemicals in the brain Neurotransmitters | Biochemical Imbalance Concept |
What drug therapy can treat Bipolar Disorder? | Lithium salts |
Depression results from a deficiency of neuronal and synaptic catecholamines (primarily Norephephrine) and mania from an excess of amines at the adrengergic receptor sites in the brain. | Biogenic Amine Hypothesis (BAH) |
excess amines | Mania |
deficiency of catecholamine (Norepinephrine) | Depression |
Affective disorder are due to decrease concentrations of serotonin | Permissive Hypothesis |
Reformation of the BAH not simply increase or decrease catecholamine but as a failure of the regulation of catacholamine activity | Dysregualtion Hypothesis |
Muscle spams, tremors, seizures, coma, renal failure | Serotonin Syndrome |
Highly bound to plasma proteins, compete with other Protein binding drugs | SSRIs |
Serotonin selective reuptake inhibitor | sertraline (Zoloft) |
An overdose of what drug can cause seizures,coma, circulatory collapse, stroke, and cerebral Hemmorage? | selegiline (Eldepryl) |
What drug can be used to treat Alcohol withdrawel? | lorazepam (Ativan) |
What drug has little tolerance on the CV side effects? | sertraline (Zoloft) |
What drug does not elicit the "cheese effect" | Selegiline (Eldepryl) |
first generation Antidepressants now considered second line | quetiapine (Seroquel) |
potentially life threatening include symptoms of high fever, unstabel BP, myoglobinemina | quetapine (Seroquel) neuroleptic malignant syndrome |
Painfule muscle spasms | Akathisia |
intractable hiccups | quetiapine (Seroquel) |
decrease REM sleep | sertraline (Zoloft) |
takes 4 to 6 weeks maxium effectiveness | sertraline (Zoloft) |
superior to TCA's and MAOIs | sertraline (Zoloft) |
painful muscle spams (Akathisia) can be treated with | Bentropine (Cogentin) and trihephendule (Artane) |
treat major depressive disorder | duloxetine (Cymbalta) |
of 0.6 to 1.5 mEq/L | Lithium therapeutic levels |
may darken urine | Enacapone |