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antiepileptic agents
Pharm
| Question | Answer |
|---|---|
| the unpleasant state of mind in which unreal or imagined dangers are anticipated | Anxiety |
| A state charcterized by an expansive, emotional state (including symptoms of extreme exitement and elation) and hyperactivity | Mania |
| A group of psychotropic agents prescribed to alleviate anxiety | Benzodiazepines |
| Emotional disorders charcterized by changes in mood | Affective Disorders |
| Classified as a monoamine oxidase inhibitor (MAOI) | Phenelzine |
| Patients on MAOIs need to be taught to avoid food that contain this substance | Tyramine |
| Antidepressants agents that block reuptake of amine neurotransmitters | Tricyclics |
| An abnormal emotional state charcterized by exaggerated fellings of sadness, melancholy, and worthlessness out of proportion to reality | Depression |
| The most frequently prescribed Benzodiazepine | Diazepam |
| The most widely used Tricyclic antidepressant | Amitriptyline |
| An atypical antipsychotic agent used to treat schizophrenia | Resperidone |
| A second-generation antidepressant | Sertraline |
| the drug of choice for mania | Lithium |
| A term used to describe a major emotional disorder that impairs the metal function of the affected individual to the extent that the individual cannot participate in every day life | Psychosis |
| Patients taking newer antipsychotic agents such as quetiapine (Seroquel) should be cautioned about which problem? | Postural hypotension |
| When starting an antidepressent therapy, How long will it take to feel better? | 4 to 6 weeks |
| Extrapyamidal effects include | spasmodic movement of limbs and the inability to sit still, parkinsonian-like symptoms (mask-like facial expressions), involuntary motor restlessness |
| Patient on MAOI therapy must avoid Tyramine containing foods in order to prevent which medical condition? | Severe hypertensive crisis |
| Abnormal levels of endogenous chemicals in the brain Neurotransmitters | Biochemical Imbalance Concept |
| What drug therapy can treat Bipolar Disorder? | Lithium salts |
| Depression results from a deficiency of neuronal and synaptic catecholamines (primarily Norephephrine) and mania from an excess of amines at the adrengergic receptor sites in the brain. | Biogenic Amine Hypothesis (BAH) |
| excess amines | Mania |
| deficiency of catecholamine (Norepinephrine) | Depression |
| Affective disorder are due to decrease concentrations of serotonin | Permissive Hypothesis |
| Reformation of the BAH not simply increase or decrease catecholamine but as a failure of the regulation of catacholamine activity | Dysregualtion Hypothesis |
| Muscle spams, tremors, seizures, coma, renal failure | Serotonin Syndrome |
| Highly bound to plasma proteins, compete with other Protein binding drugs | SSRIs |
| Serotonin selective reuptake inhibitor | sertraline (Zoloft) |
| An overdose of what drug can cause seizures,coma, circulatory collapse, stroke, and cerebral Hemmorage? | selegiline (Eldepryl) |
| What drug can be used to treat Alcohol withdrawel? | lorazepam (Ativan) |
| What drug has little tolerance on the CV side effects? | sertraline (Zoloft) |
| What drug does not elicit the "cheese effect" | Selegiline (Eldepryl) |
| first generation Antidepressants now considered second line | quetiapine (Seroquel) |
| potentially life threatening include symptoms of high fever, unstabel BP, myoglobinemina | quetapine (Seroquel) neuroleptic malignant syndrome |
| Painfule muscle spasms | Akathisia |
| intractable hiccups | quetiapine (Seroquel) |
| decrease REM sleep | sertraline (Zoloft) |
| takes 4 to 6 weeks maxium effectiveness | sertraline (Zoloft) |
| superior to TCA's and MAOIs | sertraline (Zoloft) |
| painful muscle spams (Akathisia) can be treated with | Bentropine (Cogentin) and trihephendule (Artane) |
| treat major depressive disorder | duloxetine (Cymbalta) |
| of 0.6 to 1.5 mEq/L | Lithium therapeutic levels |
| may darken urine | Enacapone |