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Exam Pharm 6
Pharm
| Question | Answer |
|---|---|
| ecessive electrical dishcharges in the nerve cell of the brain | Epilepsy |
| brief episode of abnormal activity in the brain | Seizure |
| involuntary spasmodic contractions of any (vol) muscles throughout the body, includes skeletal and facial muscles | Convulsion |
| a cause that cannot be identified and more than 50% (Idiopathic) | Primary Epilepsy |
| results from trauma, infection, cerebrovascular disorder | Secondary Epilepsy |
| starts out as either Partial or Generalized Seizures and end in No Recovery between attacks | Status Epilepticus |
| decrease polysynaptic response and block post tetanic potentiation | carbamazepine (Tegratol) |
| second most common prescribed AED | carbamazepine (Tegratol) |
| adminstered rectally for acute repeated seizures | diazepam (Valium) |
| AED Therapy | 1. Prevent spread of excessive electrical discharges from abnormal nerve cells 2.Protect surrounding normal cells |
| take with meals to reduce GI upset | Antiepileptic Agents |
| the difference between safe and toxic levels of medications | Narrow therapeutic index |
| Depresses the limit spread of a seizure discharge from its origin by suppressing the transmission of impulse from one nerve to the next | carbamazepine (Tegratol) |
| Potentiates the actions of GABA(inhibitory neurotransmitter in the brain that functions to inhibit nerve transmission in theCNS) produces sedation and muscle relaxation | diazepam (valium) |
| Benzodiazepine | diazepam (valium) |
| Bezodiazepine | lorazepam (Ativan) |
| Depresses activity in brain cells primiarily in the brainstem; selectively depresses neurons in posterior hypothalamus; decrease motor activity | Phenobarbital (Solfotonl) |
| Chronic, Progressive Disorder, Degerative disorder affects Dopamine producing neurons in the brain | Parkinson's Disease |
| Caused by imbalace of Dopamine and Ach | Parkinson's Disease |
| the location of the deficit of Dopamine and Ach is? | Substantia Nigra (basal ganglia) |
| Controls Movement | Basal Ganglia |
| A balance of Neurotransmitters equal? | Normal posture, muscle tone, and voluntary movement |
| Does not allow exogenously supplied Dopamine to enter the brain? | Blood Brain Barrier |
| Natural occuring Dopamine | Levadopa |
| Rapid swings in response to Levadopa | ON/OFF Phenomenon |
| What happens when too much Dopamine? | Dyskinesia |
| Irregular, spasmodic, involuntary movement of the limbs or facial muscle? | Chorea |
| Abnormal muscle tone in any tissue? | Dystonia |
| Dopaminergic therapy | Levodopa-carbidopa |
| Replacement therapy for Antiparkinsonian? | Levodopa-carbidopa |
| direct acting | bentropine mesylate (Cogentin) |
| Blockade of central Ach receptors in the CNS, neurotransmitters are balanced | benztropine mesylate (Cogentin) |
| Indirect acting for Antiparkinsonian Agents | selegiline (Elepryl) |
| MAOI | selegiline (Elepryl) |
| Avoid food containing tyramine | selegiline (Elepryl) |
| MAOIs breakdown catecholamines in the CNS, primarily the brain causes increase in the levels of dopaminergic stimulation in the CNS, causing accumulation at the nerve ending | selegiline (Elepryl) |
| Treatment needed when emotions affect ability to carry Normal Daily Living (ADL) | Psychotherapeutics |
| Hallmark: Loss of contact with reality | Psychoses EX: schizophrenia |
| Both mania and depression equal | Bipolar disorder |
| sense dread and fear based on past experiences by be exaggerated responses to imaginary negative situations | Anxiety |
| do not relieve bradykinesia | benztropine mesylate (Cogentin) |
Created by:
jessesandoval153
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