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Mod 6
Peripheral System Drugs
Question | Answer |
---|---|
What are the three main functions of the sympathetic nervous system? | 1.Regulation of cardiovascular system. 2.Redistributing blood 3.Compensating for loss of blood |
How does the sympathetic nervous system regulate the cardiovascular system? | •Maintaining blood flow to the brain •Redistributing blood •Compensating for loss of blood |
How does the sympathetic nervous system regulate body temperature? | •Regulates blood flow to the skin •Promotes secretion of sweat •Induces piloerection (erection of hair) |
How does the sympathetic nervous system implement the "fight-or-flight" reaction? | •Increasing heart rate and blood pressure •Shunting blood away from the skin & viscera •Dilating the bronchi •Dilating the pupils •Mobilizing stored energy |
What are the general functions of the parasympathetic nervous system? | Digestion of food, excretion of waste, control of vision, conservation of energy |
What are the specific functions of the parasympathetic nervous system? | •Slowing the heart rate •Increasing gastric secretions •Emptying the bladder & bowel •Focusing the eye for near vision •Constricting the pupil •Contracting bronchial smooth muscle |
What are the peripheral adrenergic receptor subtypes? | Alpha1, Alpha2, Beta1, Beta2, Dopamine |
What are the peripheral cholinergic receptor subtypes? | NicotinicN, NicotinicM, Muscarinic |
What are the peripheral adrenergic receptor subtypes motivated by? | Epinephrine |
What are the peripheral cholinergic receptor subtypes motivated by? | Acetycholine |
Where are NicotinicN receptors located? | All autonomic nervous system ganglia and the adrenal medulla |
Where are NicotinicM receptors located? | Neuromuscular junction |
Where are Muscarinic receptors located? | All parasympathetic target organs - Eye, Heart, Lung, Bladder, GI tract, Sweat, Sex organs & Blood vessels |
Where are the Alpha1 receptors located? | Eye, Arterioles (skin, viscera, mucous membranes), Veins, Sex organs (male), Prostatic capsule, Bladder |
Where are the Alpha2 receptors located? | Presynaptic nerve terminals |
Where are the Beta1 receptors located? | Heart, Kidneys |
Where are the Beta2 receptors located? | Arterioles (heart, lung, skeletal muscle), Bronchi, Uterus, Liver, Skeletal muscle |
Where are the dopamine receptors located? | Kidney |
NicotinicN: Ganglia & Adrenal medulla.. Function? | Stimulation of parasympathetic and sympathetic postganglionic nerves and release of epinephrine from the adrenal medulla. |
NicotinicM: Neuromuscular junction.. Function? | Contraction of skeletal muscle |
Muscarinic: Eye.. Function? | - ontraction of the ciliary muscle (focuses lens for near vision) -Contraction of iris sphincter (decreased pupil diameter, MIOSIS) |
Muscarinic: Heart.. Function? | Decreased rate |
Muscarinic: Lung.. Function? | -Constriction of bronchi -Promotion of secretions |
Muscarinic: Bladder.. Function? | -Contraction of detrusor (increases bladder pressure) -Relaxation of trigone & sphincter (allows urine to leave bladder) - Coordinated contraction of detrusor and relaxation of trigone & sphincter (causes voiding of the bladder) |
Muscarinic: GI System.. Function? | -Salivation -Increased gastric secretions -Increased intestinal tone/motility -Defecation |
Muscarinic: Sweat Glands.. Function? | Generalized sweating |
Muscarinic: Sex Organs.. Function? | Erection |
Muscarinic: Blood vessels.. Function? | Vasodilation |
Alpha1: Eye.. Function? | Contraction of the radial muscle of the iris (increases pupil size, dilation, MYDRIASIS) |
Alpha1: Arterioles: Skin, Viscera, Mucous Membranes.. Function? | Constriction |
Alpha1: Veins.. Function? | Constriction |
Alpha1: Sex organs, male.. Function? | Ejaculation |
Alpha1: Prostatic capsule.. Function? | Contraction |
Alpha1: Bladder.. Function? | Contraction of trigone & sphincter (doesn't allow uring to leave bladder) |
Alpha2: Presynaptic nerve terminals.. Function? | Inhibition of transmitter release |
Beta1: Heart.. Function? | Increased rate, force of contraction and AV conduction velocity |
Beta1: Kidney.. Function? | Release of renin |
Beta2: Arterioles (heart, lung, skeletal muscle).. Function? | Dilation |
Beta2: Bronchi.. Function? | Dilation |
Beta2.. Skeletal muscle.. Function? | Glycogenolysis |
Beta2: Uterus.. Function | Relaxation |
Beta2: Liver.. Function? | Glycogenolysis |
Dopamine: Kidney | Dilates renal blood vessels |