Busy. Please wait.

show password
Forgot Password?

Don't have an account?  Sign up 

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Didn't know it?
click below
Knew it?
click below
Don't know
Remaining cards (0)
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Dose Response

site of drug action, dose response and agonist/antagonists

How do you classify a drug? It is an agent that interacts with specific target molecules in the body and produces a physiological effect
Pharmacodynamics means: The mechanism by which drugs exert their effect on the body for a therapeutic action to occur. Includes drug-receptor interactions
Pharmacokinetics is: what the body does to the drug i.e. absorption, metabolism and excretion
The three main aspects of NON-POTENT drugs are: 1) active at high concentrations 2) little structural specificity 3) cause physical change
The three main aspects of POTENT drugs are: 1) act at low concentrations 2) structural specificity 3) act by chemical interactinon
Receptors are the site at which a ligand attached. They may be: Neurotransmitters, hormones or local factors. Activation of a receptor by these produces a response
with increased concentration of a drug, there is: increased risk of non-specific side effects
Agonists: mimic endogenous ligands, binding to a receptor and causing an effect
Antagonists: bind to a receptor and prevent the action of an agonist. Most are competitive and reersible
Drug-Receptor interaction assumes that: the effect of a drug is proportional to the fraction of receptors occupied
Efficacy is: the measure of a drug's effectiveness to produce a maximal result
Affinity: Binding of a drug to a receptor
Efficacy: Response to binding
ED50 (EC50): 50% of maximal effect
Competitive (surmountable) Antagonism: most common in therapeutic drugs. Maximal effect unchanged. agonist and antagonist compete at high affinity for receptor sites parallel shift to the right
Non-Competitive (Irreversible) Antagonism: receptor must die for effect to stop. act on receptor itself so that agonist can not bind. Max effect no longer produced
Spare receptors
Created by: KitL



Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!

"Know" box contains:
Time elapsed:
restart all cards