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RCC Rad Onc

Renal Cell Carcinoma Rad Onc

QuestionAnswer
RCC T1 Tumor <=7cm in greatest dimension, limited to the kidney
RCC T1a Tumor <= 4cm in greatest dimension, limited to the kidney
RCC T1b Tumor more than 4cm but <=7cm in greatest dimension, limited to the kidney
RCC T2 Tumor >7cm, limited to the kidney
RCC T3 Tumor extends into major veins or invades adrenal gland or perirenal and/or renal sinus fat but not beyond Gerota's fascia
RCC T3a Tumor invades adrenal gland or perirenal and/or renal sinus fat but not beyond Gerota's fascia
RCC T3b Tumor grossly extends into the renal vein or its segmental (muscle-containing) branches, or vena cava below the diaphragm
RCC T3c Tumor grossly extends into vena cava above diaphragm or invades the wall of the vena cava
RCC T4 Tumor invades beyond Gerota's fascia
RCC N1 Mets in a single regional LN
RCC N2 Mets in more than one regional LN
RCC Stage I and 5 yr OS T1N0M0. 5 yr OS 85-90%
RCC Stage II and 5 yr OS T2N0M0. 5 yr OS 65-85%
RCC Stage III (2) and 5 yr OS T3N0M0, T1-3N1M0. 5 yr OS 40-60%
RCC Stage IV (3) and 5 yr OS (2) T4N0-1M0, AnyTN2M0, Any M1. 5 yr OS 30% if only 1 metastatic site. <10% if >1 metastatic site
RCC Treatment Recommendations for Radiation No widely accepted role for adjuvant RT, although retrospective data suggests possible utility in select cases. Unresectable disease could have pre-op RT. Focal palliation of mets can be performed.
Created by: aherskovic