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Cardiac Dru.

Cardiac Drugs for Pharm Exam #2

Reabsorption at Proximal Convoluted Tubule 65% of filtered Na+ and chloride reabsorbed here -Most bicarbonate,and potassium
Reabsorption at Loop of Henle Descending: Water permeable, water drawn into Interstitial space from loop, concentrates urine
Reabsorption at DCT (early) Reabsorbs 10% of NA+ and Cl-, and water follows passively
Reabsorption at distal nephron (late DCT) -Aldosterone reabsorbs Na+ and gets rid of K+
ADH (in Collecting duct) regulates final concentration of urine. Allows collecting duct to be permeable to water. -Body reabsorbs more water; without ADH large amounts of water can leave body
Method of Diuretics -Blocks Na+ and Cl- reabsorption, which blocks passive reabsorption of H2O -If water and solutes are not reabsorbed, they are excreted from body -Drugs that act early in nephron can block the greatest amnt. of solute reabsorption
Created by: 694402933



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