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Pharmacology

QuestionAnswer
Na 135-145
K 3.5-5
Ca 9-10
Cl 95-105
Mg 1.5-2.5
Ph 2.5-4.5
Lithium Therapeutic Drug Level 0.5-1.5
Digoxin Therapeutic Drug Level 0.5-2
Theophylline Therapeutic Drug Level 10-15
Dilatin(Phenytoin) Therapeutic Drug Level 10-20
Heparin, lab test & antidote PTT (Protamine Sulfate)
Coumadin, lab test & antidote PT (Vit K)
What do you give for Tylenol overdose? Cetylcystine
What kinds of food should not be given with MAOIs? tyramine containing foods.
What are examples of foods that contain tyramine? Overripe or fermented foods. Avacados, bananas, fermented meats and sausages (salami), dried or cured fish, all cheese, yeast extract, beer, wine
BEAM (B1 selective) Betaxolol, Esmolol, Atenolol, Metoprolol
When do you take proton pump inhibitors in relation to other meds and food? Empty stomach 1 hour prior to other meds or food.
Some examples of Proton Pump Inhibitors "zole" Esmeprazole(Nexium), Omeprazole(Prilosec), Pantoprazole(Protonix)
What drug is used to lower ammonia levels in the blood? Lactulose (also used as a laxative)
Meclizine prevention of motion sickness and vertigo
Scopolamine motion sickness, nausea and vomiting after sugery
Ondansetron(Zofran) Dolasetron(Anzemet) N&V chemo and post op
Short acting insulin, when is onset & peak Regular Insulin(Humulin), (30 min)(2-4hr) (Clear)
Rapid acting insulin, onset & Peak Novolog, Humalog (5-15 min) (30-60 min)
Intermediate acting insulin (long acting), onset & peak Neutral Protamine Hagedorn (NPH) (1-2hr)(4-12hr) (Cloudy)
Order to putting 2 types of insulin in one syringe. Clear before Cloudy "Regular then Long"
Metformin Used only in Type 2 Diabetes. Only in people with good kidney function. Do not drink alcohol. SE lactic acidosis
3 G's that lower BG Glipizide, Glimepiride, Glyburide
Drug used for severe hypoglycemia when IV glucose is not available Glucagon
Hypothyroidism severe-myxedema children-cretism
Drugs for Hypothyroid Levothyroxine(T4), Liothyronine(T3), Thyroid
Hyperthyroid Graves Disease, Plummer's Disease
Drugs for Hyperthyroid Methimazole(Tapazole), Propylthiouracil(PTU)
Which antithyroid drug is safer for woman who are pregnant or breastfeeding PTU
Excess glucocorticoids Cushings, restrict Na
Unable to make corticosteriods Addison's
Drugs for Addison's (Corticosteriods) Cortisone, Hydrocortisone(drug of choice), methylprednisolone, Prednisone
Facts for Corticosteriods Give with food in AM, no grapefruit juice, weight gain, HYPERglycemia, immunosuppresent watch for signs of infection
Desmopressin, Vasopressin antidiuretic hormones, monitor edema, Na level
Growth Hormones Somatropin & Pegvisomant (adults only)
How does growth hormone effect blood glucose? GH increases blood glucose level
Potassium sparing diuretic Spironolactone
What do you need to always check when giving furosemide(lasix) K level.....Lasix can cause K level to be low
Hydrochlorothiazide First line drug for HTN, diuretic, use sunscreen
3 drugs for erectile disfunction Sildenafil(Viagra), Tadalafil(Cialis), Vardenafil(Levitra) Cause vasodilation
Tamsilosin(Flomax) outflow obstruction in males with BPH
Finasteride(Propecia)(Proscar) BPH, baldness, impotence (testosterone inhibitor)
Calcium Acetate Reduce Ph levels in patients with ESRD (with meals)
What drug stimulates RBC production Epoetin(Epogen), eat foods high in iron(meat & Eggs) do not shake vial
Cholinergic Parasympathetic (relax)
Bethanechol(Urecholine) cholinergic, urinary tract stimulant "chol"
Tolterodine(Detrol) anticholinergic, antispasmatic for overactive bladder
Propofol(Diprivan) Gen Anesth, amnesia, not pain med
Barbituates Pentobarbital, Secobarbital, Phenobarbital CNS depression anticonvulsant, sedative-hypnotic
Benzodiazepine antianxiety, sedative hypnotic, no grapefruit juice
Midazolam(Versed) Alprazolam(Xanax) Diazepam(Valium) Lorazepam(Ativan) Benzodiazepine antidote-Flumazenil
Hypnotics used for insomnia Zolpidem(Ambien), Eszopiclone(Lunesta), rapid onset, swallow whole.
Levetiracetam(Keppra) anticonvulsant
Carbidopa/Levdopa(Sinemet) anti-parkinson agent/dopamine agonist, dry mouth, dark urine & sweat, high protein meals affect,
Buspirone(BuSpar) antianxiety agent, report palpitations, chest discomfort, or faintness immediately
SSRI antidepressant used for depression, OCD, social phobias, bulimia, anorexia, panic disorder. Assess for suicide and chest discomfort
Fluoxetine(Prozac) Citalopram (Celexa) Paroxetine (Paxil) Escitalopram (Lexapro) SSRI (selective seretonin reuptake inhibitor)
Lithium Bipolar Disorder, do not limit Na intake, can cause weight gain & acne
Bupropion(Wellbutrin) antidepressant, smoking deterrent
Sibutramine(Meridia) Appetite suppressant
Modafinil(Provigil) narcolepsy, sleep apnea improves wakefullness, take in AM, no CV problems, elevate liver enzymes
Adenosine K channel opener, half life 1-2 sec, IV bolus as close to the heart as possible PSVT
K channel blockers Amiodarone Av Block, pulmonary fibrosis & Dronedarone multi channel blocker maintinence
Na channel blockers Quinidine Procainamide, Lidocaine
Amlodepine & Felodepine CCB blood vessels HTN
Diltiazem & Verapamil SA node and Blood vessels HTN & Dysrhythmia
"Pril" Ace-I cough, inc K, inc, BG, teratogenic
"sartan" ARB no renal artery stenosis
Tekturna Direct Renin Antagonist for HTN
"statins" CoA Reductase Inhibitors hypercholesterol, lower LDL raise HDL, lifelong
total cholesterol less 200
HDL greater 50
LDL less then 100
Triglycerides less 150
Primary HTN (Essential) No cause, chronic preogressive
Secondary HTN identifiable cause, can cure, lifestyle modifications
Creatinine (0.6-1.0)inc in blood stream when kidney is not working properly
Creatinine Clearance 24 hour urine test
BUN (10-20)
Clonidine centrally acting, make sleepy, dry mouth (A2 agonist)
Methyldopa A2 agonist for anxiety and HTN
Tamsulosin A1 Anatgonist BPH
Prazosin, Phentolamine, Phenoxybenzamine A1 Antagonist
bacteriacidal kill bug
bacteriastatic inhibit synthesis and growth
Vancomycin nephrotoxic (check creat), need peak (1hr after med) and trough
which cephalosporins cross the BBB Generation 3 & 4
Cefatriaxone No Ca, can cause bleeding, two diff IV sites
Drugs for TB Isoniazid(INH) & Rifampin
lethargic arousable but falling asleep
Stuprous pain for person to respond
Obtunded really have to shake to wake up
Lithium toxicity hyponeutremia, seizures
when do you use valium for a seizure when you don't know the Na level
Dilantin(Phenytoin) Discolors urine, gingival hyperplasia
WBC 3.1-11.8
HGB 12-17
HCT 36-51
Created by: 100000751146627