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week 1 phm 111
final notes
| Question | Answer |
|---|---|
| What are the 3 categories for OTC drugs by the FDA? | Generally recognized as safe and effective (GRASE), Not GRASE, cannot determine if GRASE. |
| The purity of a product means what? | The lack of contamination from environmental factors. |
| Potency refers to what? | The strength of the drug. |
| Bioavailability is what? | The % and rate of a drug that is absorbed and transported to the affected site. |
| Efficacy is the ability to what? | Of a drug to produce the desired effects in the body. |
| FDA approval stages for OTC drugs | Phase 1, advisors evaluate the drug, phase 2 a review is done by the FDA and phase 3 is when the monograph is published on the drug. |
| Asprin has been associated with what syndome | Reye's syndrome |
| What substance is used to treat od of asprin? | Activated Charcoal. |
| How do antihistamines work? | They block the histamine receptors. |
| You should avoid what substance while taking sleep aids? | Alcohol. |
| What things two things are used to treat acid in the stomach? | h2 antagonists and proton pump inhibitors. |
| What factors cause errors to occur with medications? | ambiguous strength labeled on drug containers excessive workload failure to transcribe properly handwriting, calculations, labeling errors and look-a-like drugs |
| Warfaron is given for what? | to prevent clots that can cause strokes and heart attacks |
| The most common od's are? | herpain, insulin and KCi |
| Many errors occur do to suffix errors. T or F? | T. |
| Warnings in a drug box are called? | Black box warnings |
| The black box warnings inform you of what? | any serious adverse effects. |
| ASHP is responsible for what of our program? | The curriculum. |
| The steps in our reconciliation are what? | Verification, clarification and reconciliation. |
| The nervous system consists of what? | Sensory neurons posistioned throughout the body. |
| What are the four major functions of the NS are what? | Transmisson of impilse from the sensory neurons to the CNS, interpretation of impluses sent to the CNS and transmission of a response, cordination of the activities and maintance of homeostasis. |
| The adult brain weighs what? | 1.4 kg (3lbs) |
| The brain contains 100 billion neurons. T or F? | True. |
| the somatic system does what? | Relays motor impluses to skeletal muscles throughout the body. |
| The autonomic does what? | transmits motor impluses to smooth muscle. |
| What are dendrites? | the extensions that receives electrical impluses. |
| Special insulations is called what? | The myelin sheath. |
| Bundle of cell bodies are called what? | ganglions. |
| The electrical impluses are transmitted from one neuron to another is called what? | Neurotransmitters. |
| The primary function of the afferent branch is to what? | transfer information via electrical impluse fromt he peripheral area to the CNS. |
| Efferents are the ______ neurons. | Motor. |
| The three stages of nerve transmission are what? | polarization, depolarization and repolarization. |
| What are the meninges? | thin covering lining the inside of the bones. |
| The PNS is further divided into what two systems?` | autonomic and somatic. |
| The sympathetic divisons is responsible for what? | The fight or flight. |
| The main organs where the sympathetic system is activated are what? | Heart, lungs, blood vessels, digestive system, urinary system, liver, eyes, adrenal medulla and sweat glands. |
| The main neurotransmitters of the sympathetic system are what? | norepinephrine and epinephrine. |
| The main neurotransmitter of the parasympathetic system is what? | acetylcholine. |
| Two types of cholinergic agents are what? | parasympathomimetics and anticholinergics. |
| Central acting medications do what? | Depress the CNS |
| Diirect acting meds do what? | Work directly on the muscles. |
| Myasthenia Gravis is what? | A rare autoimmune disorder that affects the transmisson of electrical impluses fromt he CNS to the muscles throughout the body. |
| A stroke is a what? | A disruption of the blood flow or the leakage of blood outside the vessel walls. |
| What is epilepsy? | A seizure disorder. |