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CPK
Drug Receptor/Effect
Target Organ | Drug receptor | Agonist effect | Antagonist effect |
---|---|---|---|
Heart rate (sympathetic) | Beta-1 & Beta-2 | Increase | Decrease |
Heart rate (cholinergic) | Cholinergic | Decrease | Increase |
Heart (contractibility) | Beta-1 and Beta-2 | Increase | Decreaese |
Blood vessels (Arterial-alpha) | Alpha-1 | Vasoconstriction | ------ |
Blood vessels (Arterial -beta) | Beta-2 | Vasodilation | ------ |
Lungs (bronchioles-sympathetic) | Beta-2 | Bronchodilation | Bronchoconstriction |
Lungs (bronchioles-cholinergic) | Cholinergic | Bronchoconstriction | Bronchodilation |
Lungs (Airway secretions) | Cholinergic | Increase | Decrease |
Eye (Pupils-sympathetic) | Alpha-1 | Mydriasis | Miosis |
Eye (Pupils-cholinergic) | Cholinergic | Miosis | Mydriasis |
Lens of Eye (Accommodation) | Cholinergic | ------ | Decrease (blurred vision) |
Eye (Lacrimation) | Cholinergic | ------ | Decrease (dry eyes) |
Mouth (Salivation) | Cholinergic | ------ | Decrease (dry mouth) |
Stomach (Acid secretion) | Cholinergic | Increase | Decrease |
GI Tract (Motility) | Cholinergic | Increase | Decrease |
Bladder Wall (Detrusor Muscle) | Cholinergic | Contraction (enhance urination) | Relaxation (inhibit urination) |
Bladder Sphincter (Sympathetic) | Alpha-1 | Constriction (inhibit urination) | Relaxation (enhance urination) |
Bladder Sphincter (Cholinergic) | Cholinergic | Relaxation (enhance urination) | Contraction (inhibit urination) |
Uterus (labor contractions) | Beta-2 | Decrease (Inhibit labor) | ------ |
Skin (Sweat) | Cholinergic | Increase | Decrease |