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Drug Receptor/Effect

Target OrganDrug receptorAgonist effectAntagonist effect
Heart rate (sympathetic) Beta-1 & Beta-2 Increase Decrease
Heart rate (cholinergic) Cholinergic Decrease Increase
Heart (contractibility) Beta-1 and Beta-2 Increase Decreaese
Blood vessels (Arterial-alpha) Alpha-1 Vasoconstriction ------
Blood vessels (Arterial -beta) Beta-2 Vasodilation ------
Lungs (bronchioles-sympathetic) Beta-2 Bronchodilation Bronchoconstriction
Lungs (bronchioles-cholinergic) Cholinergic Bronchoconstriction Bronchodilation
Lungs (Airway secretions) Cholinergic Increase Decrease
Eye (Pupils-sympathetic) Alpha-1 Mydriasis Miosis
Eye (Pupils-cholinergic) Cholinergic Miosis Mydriasis
Lens of Eye (Accommodation) Cholinergic ------ Decrease (blurred vision)
Eye (Lacrimation) Cholinergic ------ Decrease (dry eyes)
Mouth (Salivation) Cholinergic ------ Decrease (dry mouth)
Stomach (Acid secretion) Cholinergic Increase Decrease
GI Tract (Motility) Cholinergic Increase Decrease
Bladder Wall (Detrusor Muscle) Cholinergic Contraction (enhance urination) Relaxation (inhibit urination)
Bladder Sphincter (Sympathetic) Alpha-1 Constriction (inhibit urination) Relaxation (enhance urination)
Bladder Sphincter (Cholinergic) Cholinergic Relaxation (enhance urination) Contraction (inhibit urination)
Uterus (labor contractions) Beta-2 Decrease (Inhibit labor) ------
Skin (Sweat) Cholinergic Increase Decrease
Created by: tlaugherty