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Pharmco exam 4 drug

drugs/indications for exam 4 in Pharmacology

QuestionAnswer
SMX/TMP (Bactrim) Sulfonamide, UTI, bacterial respiratory infection, GI infection, Pneumocystic jiroveci, prohylaxis of neutopenic patients
Penicillin G penicillin abx
Penicillin V penicillin abx
Methicillin penicillin abx
Nafcillin penicillin abx
Oxacillin penicillin abx
Dicloxacillin penicillin abx
Ampicillin penicillin abx
Amoxicillin penicillin abx
Ticaricillin penicillin abx
Peperacillin penicillin abx
1st generation Cephalosporins gram positive infections (staph, strep PEcK)
2nd generation cephalosporins HEN PEcK, po for otitis, sinusitis, respiratory tract infections
3rd generation cephalosporins shouldn't be used routinely, gram neg/pos, DOC for treating meingitis caused by gram neg (S pneumonae, H influ, Neisseria), neisseria gonorrhae, H influenzae, klebsiella, proteus, salmonella, serratia
4th generation cephalosporins highly resistant to B-lactamases, penetrates CSF, activity against pseudomonas= ceftazidine
5th generation only cephalosporin with activity against MRSA
Imipenem Carbapenem Abx, B-lactam abx, broad spectrum
Meropenem Carbapenem Abx, B-lactam abx, broad spectrum
Ertapenem Carbapenem Abx, B-lactam abx, broad spectrum
Doripenem Carbapenem Abx, B-lactam abx, broad spectrum
Aztreonam monbactum, bactericidal, narrow spectrum, highly resistant to B-lactamases, only gram neg aerobic
Vancomycin MRSA, C diff, serious infections in those allergic to penicillins
Daptomycin lipopeptide, resistant gram pos (MRSA, MSSA, VRE, penresistant)
Chlortetracycline Tetracycline
Oxytetracycline Tetracycline
Tetracycline Tetracycline
Demeclocycline Tetracycline
Methacycline Tetracycline
Doxycycline Tetracycline
Minocycline Tetracycline
Tigecycline (Tygacil) Active vs TTC resistant strains, bacteriostatic, IV only
Chloramphenicol Broad spectrum, bacteriostatic, not used anymore due to infants not being able to conjugate with glucuronic acid (gray baby syndrome)
Erythromycin Macrolide ABx
Clarithromycin Macrolide ABx
Azithromycin Macrolide ABx
Streptomycin Aminoglycoside, used for plague, tularemia and TB in addition to normal uses
Neomycin Aminoglycoside
Kanamycin Aminoglycoside
Amikacin Aminoglycoside
Gentamycin Aminoglycoside
Tobramycin Aminoglycoside
Sisomycin Aminoglycoside
Netilomycin Aminoglycoside
Spectinomycin Used to treat gonorrhea
Clindamycin S aureus, S progenes, B fragilis, C tetani, prophylaxis of endocarditis in dental procedures if allergic to penicillin
Linezolid (Zyvox) an oxazolidinone, synthetic antimicrobial, used against MRSA
Chloroquine Antimalarial, check for bull's eye maculopathy
Mefloquine antimalarial, active against most chloroquine-resistant strains
Quinine antimalarial, from plant source, given IV (cerebral malaria), not really available in US
Primaquine Antimalarial, works in RBC stages, can be used against other parasites too
Malarone (atovaquone +proguanil) anti-malarial (prevention and treatment), active against chloroquine-resistant strains, atovaquone is an inhibitor of electron transport, proguanil is a dihydrofolate reductase inhibitor
Pyrimethamine/Sulfadoxine (Fansidar) antimalarial, not as good as others
CoArtem (artemether+ lumefantrine) antimalarial, new, used in developing countries
Pentamidine antiparasitic,given IV for treatment of PCP in Aids patients allergic to sulfa drugs
Created by: Kachmiel
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