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Pharmco exam 4 drug
drugs/indications for exam 4 in Pharmacology
| Question | Answer |
|---|---|
| SMX/TMP (Bactrim) | Sulfonamide, UTI, bacterial respiratory infection, GI infection, Pneumocystic jiroveci, prohylaxis of neutopenic patients |
| Penicillin G | penicillin abx |
| Penicillin V | penicillin abx |
| Methicillin | penicillin abx |
| Nafcillin | penicillin abx |
| Oxacillin | penicillin abx |
| Dicloxacillin | penicillin abx |
| Ampicillin | penicillin abx |
| Amoxicillin | penicillin abx |
| Ticaricillin | penicillin abx |
| Peperacillin | penicillin abx |
| 1st generation Cephalosporins | gram positive infections (staph, strep PEcK) |
| 2nd generation cephalosporins | HEN PEcK, po for otitis, sinusitis, respiratory tract infections |
| 3rd generation cephalosporins | shouldn't be used routinely, gram neg/pos, DOC for treating meingitis caused by gram neg (S pneumonae, H influ, Neisseria), neisseria gonorrhae, H influenzae, klebsiella, proteus, salmonella, serratia |
| 4th generation cephalosporins | highly resistant to B-lactamases, penetrates CSF, activity against pseudomonas= ceftazidine |
| 5th generation | only cephalosporin with activity against MRSA |
| Imipenem | Carbapenem Abx, B-lactam abx, broad spectrum |
| Meropenem | Carbapenem Abx, B-lactam abx, broad spectrum |
| Ertapenem | Carbapenem Abx, B-lactam abx, broad spectrum |
| Doripenem | Carbapenem Abx, B-lactam abx, broad spectrum |
| Aztreonam | monbactum, bactericidal, narrow spectrum, highly resistant to B-lactamases, only gram neg aerobic |
| Vancomycin | MRSA, C diff, serious infections in those allergic to penicillins |
| Daptomycin | lipopeptide, resistant gram pos (MRSA, MSSA, VRE, penresistant) |
| Chlortetracycline | Tetracycline |
| Oxytetracycline | Tetracycline |
| Tetracycline | Tetracycline |
| Demeclocycline | Tetracycline |
| Methacycline | Tetracycline |
| Doxycycline | Tetracycline |
| Minocycline | Tetracycline |
| Tigecycline (Tygacil) | Active vs TTC resistant strains, bacteriostatic, IV only |
| Chloramphenicol | Broad spectrum, bacteriostatic, not used anymore due to infants not being able to conjugate with glucuronic acid (gray baby syndrome) |
| Erythromycin | Macrolide ABx |
| Clarithromycin | Macrolide ABx |
| Azithromycin | Macrolide ABx |
| Streptomycin | Aminoglycoside, used for plague, tularemia and TB in addition to normal uses |
| Neomycin | Aminoglycoside |
| Kanamycin | Aminoglycoside |
| Amikacin | Aminoglycoside |
| Gentamycin | Aminoglycoside |
| Tobramycin | Aminoglycoside |
| Sisomycin | Aminoglycoside |
| Netilomycin | Aminoglycoside |
| Spectinomycin | Used to treat gonorrhea |
| Clindamycin | S aureus, S progenes, B fragilis, C tetani, prophylaxis of endocarditis in dental procedures if allergic to penicillin |
| Linezolid (Zyvox) | an oxazolidinone, synthetic antimicrobial, used against MRSA |
| Chloroquine | Antimalarial, check for bull's eye maculopathy |
| Mefloquine | antimalarial, active against most chloroquine-resistant strains |
| Quinine | antimalarial, from plant source, given IV (cerebral malaria), not really available in US |
| Primaquine | Antimalarial, works in RBC stages, can be used against other parasites too |
| Malarone (atovaquone +proguanil) | anti-malarial (prevention and treatment), active against chloroquine-resistant strains, atovaquone is an inhibitor of electron transport, proguanil is a dihydrofolate reductase inhibitor |
| Pyrimethamine/Sulfadoxine (Fansidar) | antimalarial, not as good as others |
| CoArtem (artemether+ lumefantrine) | antimalarial, new, used in developing countries |
| Pentamidine | antiparasitic,given IV for treatment of PCP in Aids patients allergic to sulfa drugs |
Created by:
Kachmiel
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