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Pharm 24 <3 Contract


Cardiac glycoside that increases inotropy for Systolic heart fail, SVT. SE: arrhythmia, agitation, fatigue, yellow-green halo around visual images. Contra: Ventricular arrhythmia. w Beta-blockers, risk of AV block; w hypokalemia, toxicity. Digoxin, Digitoxin (hepatic metab, for pts w bad kidneys)
Beta-agonists inc cAMP-> inc inotropy, chronotropy and lusitropy for Heart shock. SE: wide QRS, arrhythmia, hypotension (vasodilate periph, high doses vasoconstrict). Contra: Pheochromocytoma. Dopamine
Beta-agonists inc cAMP-> inc inotropy, chronotropy and lusitropy for Heart shock. SE: less frequent arrhythmias than Dopamine. Contra: hypertrophic subaortic stenosis. Sympathomimetic inotrope of choice for pts w acute cardiogenic circ fail Dobutamine
Nonselective agonist at Beta 1 and 2 and Alpha 1 and 2 for Bronchospasm, anaphylactic shock, cardio resuscitation. SE: arrhythmia, cerebral hemorrhage, HA, tremor. Contra: labor, angle close glaucoma, arrhythmia. high dose-> tachycardia Epinephrine
Nonselective agonist at Beta 1 and Alphas 1 and 2 for Blood pressure support in acute shock. SE: arrhythmia, cerebral hemorrhage, tremor. Contra: Periph vasc thrombosis, hypoxia, hypercapnia. Norepinephrine
Nonselective Beta 1 and 2 agonists inc cAMP-> inc inotropy, chronotropy and lusitropy for Emergency tx arrhythmia, Atropine-resist bradycardia, bronchospasm (inhaled). SE: arrhythmia, cerebral hemorrhage, tremor. Contra: digitalis tox, angina pectoris. Isoproterenol
PDE Inhib inc cAMP-> inc inotropy, lusitropy; also dec preload and afterload for short term tx of failing circulation in pts refract to conventional tx. SE: vent arrhythmia, thrombocytopenia. Inamrinone (thrombocytopenia), Milrinone (mortality)
Created by: Jakphooey



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