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CNS stimulants1
Sensory & Neuro
Question | Answer |
---|---|
Amphetamine names | Adderall, Desoxyn, Dexedrine |
Amphetamine action | For ADHD and narcolepsy. increase release of norepinephrine and dopamine to increase alertness, energy and mood |
Amphetamine side affects | insomnia and nervousness. can cause a tolerance |
Amphetamine instructions | take earlier to prevent insomnia, caffeine potentiates the affects, vitamin C decreases the affects |
Methylphenidate names | Ritalin, Concerta, Focalin |
Methylphenidate action | same as amphetamines |
Methylphenidate side affects | insomnia, nervousness, increased HR and BP |
Methylphenidate instructions | take earlier to prevent insomnia, don't take with caffeine |
Non-amphetamine names | Provigil and Nuvigil |
Non-amphetamine action | for narcolepsy. |
Non-amphetamine side affects | diarrhea, nausea, and minor CNS affects (headache, tachycardia, and HTN) |
Non-amphetamine instructions | take in the morning with food, may increase levels of warfarin |
Dopamine-replacement drug (DRD) names | levodopa and Sinemet |
DRD action | for Parkinson's. crosses blood-brain barrier and is converted to dopamine |
DRD side affects | Nausea, vomiting, orthostatic or postural hypotension |
DRD instructions | gradually increase dose, take with food, avoid high protein foods because they decrease the effect |
Direct-acting dopamine receptor agonist (DADRA) names | Mirapex, Requip |
DADRA actions | for Parkinson's. bind to dopamine receptors and mimic actions of dopamine |
DADRA side affects | similar to DRD |
DADRA instructions | give with food, if giving for restless leg syndrome give 3 hours before bed, don't take with alcohol or CNS depressants |
MAOI names | Eldepryl and Azilect |
MAOI actions | for Parkinson's and major depression. inhibits monoamine oxidase to decrease breakdown of neurotransmitters |
MAOI side affects | Insomnia, hypertensive crisis, orthostatic hypotension |
MAOI instructions | give before morning meal, take last dose of the day by noon to prevent insomnia |
Cholinesterase inhibitor names | Aricept and Exelon |
Cholinesterase inhibitor action | for Alzheimer's. prevents the breakdown of acetylcholine by inhibiting cholinesterase |
Cholinesterase inhibitor side affects | nausea, GI symptoms, insomnia, dizziness, headaches, and syncope |
Cholinesterase inhibitor instructions | give with food, watch for GI bleed, give at bedtime |
Immunomodulator names | Avonex, Rebif, and Capaxone |
Immunomodulator actions | for multiple sclerosis. inhibits the movement of leukocytes across the blood-brain barrier to protect myelin |
Immunomodulator side affects | flu-like symptoms such as headache, fever, and chills; bone marrow suppression |
Immunomodulator instructions | gradually increase dose, NSAIDs for flu-like symptoms |
Serotonin agonist names | Imitrex and Zomig. Generic names end in "triptan" |
Serotonin agonist actions | for migraines. causes vasoconstriction and prevents inflammatory response |
Serotonin agonist side affects | chest pressure or heaviness, |