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CNS stimulants1
Sensory & Neuro
| Question | Answer |
|---|---|
| Amphetamine names | Adderall, Desoxyn, Dexedrine |
| Amphetamine action | For ADHD and narcolepsy. increase release of norepinephrine and dopamine to increase alertness, energy and mood |
| Amphetamine side affects | insomnia and nervousness. can cause a tolerance |
| Amphetamine instructions | take earlier to prevent insomnia, caffeine potentiates the affects, vitamin C decreases the affects |
| Methylphenidate names | Ritalin, Concerta, Focalin |
| Methylphenidate action | same as amphetamines |
| Methylphenidate side affects | insomnia, nervousness, increased HR and BP |
| Methylphenidate instructions | take earlier to prevent insomnia, don't take with caffeine |
| Non-amphetamine names | Provigil and Nuvigil |
| Non-amphetamine action | for narcolepsy. |
| Non-amphetamine side affects | diarrhea, nausea, and minor CNS affects (headache, tachycardia, and HTN) |
| Non-amphetamine instructions | take in the morning with food, may increase levels of warfarin |
| Dopamine-replacement drug (DRD) names | levodopa and Sinemet |
| DRD action | for Parkinson's. crosses blood-brain barrier and is converted to dopamine |
| DRD side affects | Nausea, vomiting, orthostatic or postural hypotension |
| DRD instructions | gradually increase dose, take with food, avoid high protein foods because they decrease the effect |
| Direct-acting dopamine receptor agonist (DADRA) names | Mirapex, Requip |
| DADRA actions | for Parkinson's. bind to dopamine receptors and mimic actions of dopamine |
| DADRA side affects | similar to DRD |
| DADRA instructions | give with food, if giving for restless leg syndrome give 3 hours before bed, don't take with alcohol or CNS depressants |
| MAOI names | Eldepryl and Azilect |
| MAOI actions | for Parkinson's and major depression. inhibits monoamine oxidase to decrease breakdown of neurotransmitters |
| MAOI side affects | Insomnia, hypertensive crisis, orthostatic hypotension |
| MAOI instructions | give before morning meal, take last dose of the day by noon to prevent insomnia |
| Cholinesterase inhibitor names | Aricept and Exelon |
| Cholinesterase inhibitor action | for Alzheimer's. prevents the breakdown of acetylcholine by inhibiting cholinesterase |
| Cholinesterase inhibitor side affects | nausea, GI symptoms, insomnia, dizziness, headaches, and syncope |
| Cholinesterase inhibitor instructions | give with food, watch for GI bleed, give at bedtime |
| Immunomodulator names | Avonex, Rebif, and Capaxone |
| Immunomodulator actions | for multiple sclerosis. inhibits the movement of leukocytes across the blood-brain barrier to protect myelin |
| Immunomodulator side affects | flu-like symptoms such as headache, fever, and chills; bone marrow suppression |
| Immunomodulator instructions | gradually increase dose, NSAIDs for flu-like symptoms |
| Serotonin agonist names | Imitrex and Zomig. Generic names end in "triptan" |
| Serotonin agonist actions | for migraines. causes vasoconstriction and prevents inflammatory response |
| Serotonin agonist side affects | chest pressure or heaviness, |
Created by:
bergste
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