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CNS stimulants1

Sensory & Neuro

Amphetamine names Adderall, Desoxyn, Dexedrine
Amphetamine action For ADHD and narcolepsy. increase release of norepinephrine and dopamine to increase alertness, energy and mood
Amphetamine side affects insomnia and nervousness. can cause a tolerance
Amphetamine instructions take earlier to prevent insomnia, caffeine potentiates the affects, vitamin C decreases the affects
Methylphenidate names Ritalin, Concerta, Focalin
Methylphenidate action same as amphetamines
Methylphenidate side affects insomnia, nervousness, increased HR and BP
Methylphenidate instructions take earlier to prevent insomnia, don't take with caffeine
Non-amphetamine names Provigil and Nuvigil
Non-amphetamine action for narcolepsy.
Non-amphetamine side affects diarrhea, nausea, and minor CNS affects (headache, tachycardia, and HTN)
Non-amphetamine instructions take in the morning with food, may increase levels of warfarin
Dopamine-replacement drug (DRD) names levodopa and Sinemet
DRD action for Parkinson's. crosses blood-brain barrier and is converted to dopamine
DRD side affects Nausea, vomiting, orthostatic or postural hypotension
DRD instructions gradually increase dose, take with food, avoid high protein foods because they decrease the effect
Direct-acting dopamine receptor agonist (DADRA) names Mirapex, Requip
DADRA actions for Parkinson's. bind to dopamine receptors and mimic actions of dopamine
DADRA side affects similar to DRD
DADRA instructions give with food, if giving for restless leg syndrome give 3 hours before bed, don't take with alcohol or CNS depressants
MAOI names Eldepryl and Azilect
MAOI actions for Parkinson's and major depression. inhibits monoamine oxidase to decrease breakdown of neurotransmitters
MAOI side affects Insomnia, hypertensive crisis, orthostatic hypotension
MAOI instructions give before morning meal, take last dose of the day by noon to prevent insomnia
Cholinesterase inhibitor names Aricept and Exelon
Cholinesterase inhibitor action for Alzheimer's. prevents the breakdown of acetylcholine by inhibiting cholinesterase
Cholinesterase inhibitor side affects nausea, GI symptoms, insomnia, dizziness, headaches, and syncope
Cholinesterase inhibitor instructions give with food, watch for GI bleed, give at bedtime
Immunomodulator names Avonex, Rebif, and Capaxone
Immunomodulator actions for multiple sclerosis. inhibits the movement of leukocytes across the blood-brain barrier to protect myelin
Immunomodulator side affects flu-like symptoms such as headache, fever, and chills; bone marrow suppression
Immunomodulator instructions gradually increase dose, NSAIDs for flu-like symptoms
Serotonin agonist names Imitrex and Zomig. Generic names end in "triptan"
Serotonin agonist actions for migraines. causes vasoconstriction and prevents inflammatory response
Serotonin agonist side affects chest pressure or heaviness,
Created by: bergste



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